New England Journal of Medicine (NEJM) Audio Summaries Podcasts

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NEJM This Week - December 15, 2011 This summary covers the issue of December 15, 2011. Featured are articles on niacin in patients with low HDL receiving statins, dronedarone in permanent atrial fibrillation, CPAP for the metabolic syndrome and sleep apnea, hospital admission rates and rehospitalizations, a new federal program to wire the health system, and nudging neuropathy through disease genes; a review article on catheter ablation for atrial fibrillation; a case report of a man with diarrhea and weakness; and Perspect ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 8, 2011 This summary covers the issue of December 8, 2011. Featured are articles on three months of rifapentine and isoniazid for latent tuberculosis, apixaban vs. enoxaparin for thromboprophylaxis, norovirus vaccine against experimental Norwalk illness, and multiple sclerosis and cortical lesions; review articles on a request for abortion and on the pathogenesis of rheumatoid arthritis; a case report of an infant with recurrent tachypnea and respiratory distress; and Perspective articles on the ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 1, 2011 This summary covers the issue of December 1, 2011. Featured are articles on low-dose interleukin-2 in chronic GVHD, low-dose interleukin-2 in HCV vasculitis, statins for regression of coronary atherosclerosis, full drug coverage after myocardial infarction, and immunosuppression and stroke; review articles on genes, genomes, and cardiovascular disease and on systemic lupus erythematosus; a Clinical Problem-Solving article describing a hidden solution; and Perspective articles on habits of ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 24, 2011 This summary covers the issue of November 24, 2011. Featured are articles on treating obesity in primary care practice, anticoagulant regimens for non-ST-elevation myocardial infarction, daily or intermittent budesonide for recurrent wheezing, and hospitalizations for adverse drug events; a review article on screening for prostate cancer; a case report of a woman with shortness of breath and chest pain; and Perspective articles on screening for prostate cancer and on the MCAT. Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 17, 2011 This summary covers the issue of November 17, 2011. Featured are articles on the first results for malaria vaccine in African children; childhood adiposity and cardiovascular risk; maintenance therapy in lupus nephritis; ADHD drugs and serious cardiovascular events; and beta-cell failure, stress, and type 2 diabetes; a review article on extracorporeal membrane oxygenation for ARDS in adults; a case report of a woman with postpartum leukocytosis and gram-positive bacteremia; and Perspectiv ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 10, 2011 This summary covers the issue of November 10, 2011. Featured are articles on the E. coli outbreak in Germany, N-acetylcysteine in alcoholic hepatitis, and early liver transplantation for alcoholic hepatitis; review articles on sudden, unexpected death in epilepsy and on the human plasma lipidome; a case report of a man with memory loss and partial seizures; and Perspective articles on the final rule for the Medicare shared savings, on harnessing electronic data for safer care, on evidenc ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 3, 2011 This summary covers the issue of November 3, 2011. Featured are articles on a CFTR potentiator in treatment of cystic fibrosis, inducible suicide of GVHD-causing T cells, prophylaxis in hemophilia with inhibitors, C. difficile infection and colonization, the Medicare Health Support Disease-Management Pilot, and wrestling against the failing heart; a review article on ulcerative colitis; a Clinical Problem-Solving article on a bird's-eye view of fever; and Perspective articles on the short ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 27, 2011 This summary covers the issue of October 27, 2011. Featured are articles on small-airway obstruction and emphysema in COPD; HPV vaccine, anal HPV, and Intraepithelial neoplasia; briakinumab versus methotrexate for psoriasis; and persistence of hormonal adaptations to weight loss; review articles on depression during pregnancy and on genomics and autoimmune disease; a case report of a man with hypophosphatemia; and Perspective articles on rivaroxaban for nonvalvular atrial fibrillation, on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 20, 2011 This summary covers the issue of October 20, 2011. Featured are articles on the timing of antiretroviral therapy for HIV and tuberculosis; immunity and ADAM17; neighborhood, obesity, and diabetes; and fighting the flu; a review article on panretinal photocoagulation for proliferative retinopathy; a case report of a man with recurrent pancreatitis; and Perspective articles on defining essential health benefits, on medical device innovation, and on the supply-side economics of abortion. Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 13, 2011 This summary covers the issue of October 13, 2011. Featured are articles on the incidence of adenocarcinoma in Barrett's esophagus, RNA splicing defects in ring sideroblasts, bisphosphonates in early-stage breast cancer, influenza vaccine with MF59 adjuvant in children, and "Pay for Delay" settlements of patent disputes; a review article on adult primary care after childhood leukemia; a case report of a man with oligometastatic lung cancer; and Perspective articles on bariatric surgery in ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 5, 2011 This summary covers the issue of October 6, 2011. Featured are articles on adjuvant trastuzumab in HER2-positive breast cancer, acyclovir and neurodevelopment after neonatal herpes, oral teriflunomide for relapsing multiple sclerosis, adverse outcomes in women exposed in utero to DES, and the uncertain future of Medicare and GME; a review article on filaggrin mutations and skin disease; a Clinical Problem-Solving article on a man who presented to the emergency department with shaking chil ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 29, 2011 This summary covers the issue of September 29, 2011. Featured are articles on GLCCI1 in asthma response to glucocorticoid therapy, change in FEV1 over time in COPD, a randomized trial of cytisine for smoking cessation, intravenous immune globulin for neonatal sepsis, health care transitions among nursing home residents, and restrictions on the use of prescribing data for drug promotion; a review article on treating smokers in the health care setting; a case report of a woman with renal fa ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 22, 2011 This summary covers the issue of September 22, 2011. Featured are articles on a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis, efficacy of lebrikizumab in patients with asthma, hemodialysis and interdialytic risks, rotavirus vaccine and health care for diarrhea, reforming regulations for human-subject research, and mounting a mucosal immune response; a review article on hepatocellular carcinoma; a case report of a woman with cardiac and renal failure; and Perspective articles ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 15, 2011 This summary covers the issue of September 15, 2011. Featured are articles on apixaban versus warfarin in atrial fibrillation, stenting for intracranial artery stenosis, assessing a blood-stage malaria vaccine, and response-guided combination treatment for HCV; review articles on breast-cancer screening and on genomics, health care, and society; a case report of a man with pemphigus vulgaris and lung nodules; and Perspective articles on mental health and addiction care under the ACA and o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 8, 2011 This summary covers the issue of September 8, 2011. Featured are articles on rivaroxaban versus warfarin in atrial fibrillation, genes and daptomycin resistance in enterococci, obesity and risk of death among black women, health care spending and quality in year 1 of the AQC, and regulatory T cells and hematopoietic transplantation; review articles on drug-resistant epilepsy and on Mendelian disorders of membrane trafficking; a case report of a boy with abdominal pain and weight loss; and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 1, 2011 This summary covers the issue of September 1, 2011. Featured are articles on rhythm analysis in out-of-hospital cardiac arrest, an impedance threshold device in cardiac arrest, a functional element necessary for fetal hemoglobin silencing, distinctive diarrheal illness with cord-blood stem cells, EHRs and quality of diabetes care, and finding the meaning in meaningful use; a review article on care of the adult patient after sexual assault; a Clinical Problem-Solving article describing a p ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - August 25, 2011 This summary covers the issue of August 25, 2011. Featured are articles on azithromycin for prevention of COPD exacerbations, apixaban after acute coronary syndrome, origins of the E. coli strain in the German gastroenteritis outbreak, genome sequence of the E. coli in Germany, the tumor response to modified autologous T cells, and systemic lupus erythematosus and the neutrophil; a review article on thrombopoietin-receptor agonists for immune thrombocytopenia; a case report of a boy with ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - August 18, 2011 This summary covers the issue of August 18, 2011. Featured are articles on preventing intraoperative awareness in high-risk patients, Salmonella Typhimurium infection and peanut products, somatic mutation and the Proteus syndrome, IL-36-receptor antagonist in pustular psoriasis, malpractice risk according to physician specialty, and medical malpractice in the military; a review article on resistance to anti-HIV drug therapy; a case report of a woman with anemia and paraspinal masses; and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - August 11, 2011 This summary covers the issue of August 11, 2011. Featured are articles on preventing HIV-1 infection with antiretroviral therapy, parenteral nutrition in critically ill adults, intrapleural t-PA and DNase in pleural infection, linaclotide in chronic constipation, and cancer cachexia and fat-muscle physiology; a review article on oxygen sensing, homeostasis, and disease; a case report of a man with headache, memory loss, and confusion; and Perspective articles on fibrates in the treatment ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - August 4, 2011 This summary covers the issue of August 4, 2011. Featured are articles on lung-cancer mortality and low-dose CT screening, CYP24A1 mutations and infantile hypercalcemia, a new pathogenic ehrlichia species, horse vs. rabbit ATG in aplastic anemia, and Canada’s Supreme Court and the "global baby"; a review article on chronic hypertension in pregnancy; a Clinical Problem-Solving article on looking at the whole picture; and Perspective articles on developing the nation's biosimilars program ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - July 28, 2011 This summary covers the issue of July 28, 2011. Featured are articles on MYO1E mutations and childhood familial focal segmental glomerulosclerosis, Wnt signaling and Dupuytren's disease, desensitization in HLA-incompatible kidney recipients, bardoxolone methyl in chronic kidney disease with type 2 diabetes, protective effect of natural rotavirus infection, and optic cup formation; a review article on genomes of microbes; a case report of a pregnant woman with placenta accreta; and Perspec ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - July 21, 2011 This summary covers the issue of July 21, 2011. Featured are articles on ABVD vs. BEACOPP for Hodgkin’s lymphoma, carotid intima-media thickness and cardiovascular events, bronchiolitis in soldiers returning from Iraq and Afghanistan, and different T cell subsets and distinct skin diseases; a review article on febrile urinary tract infections in children; a case report of a man with a rash, arthritis, and ocular erythema; and Perspective articles on the e-cigarette, on smoking and menta ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - July 14, 2011 This summary covers the issue of July 14, 2011. Featured are articles on radiotherapy and androgen deprivation in prostate cancer; albuterol, placebo, sham acupuncture, or no intervention in asthma; dendritic-cell deficiency and IRF8; and SHANK3, the synapse, and autism; review articles on rapid-response teams and on hemostasis in chronic liver disease; a case report of a man with ALK-positive adenocarcinoma of the lung; and Perspective articles on 5-alpha-reductase inhibitors and prostat ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - July 7, 2011 This summary covers the issue of July 7, 2011. Featured are articles on new regimens to prevent TB in adults with HIV, isoniazid against TB in HIV-exposed children, nesiritide in acute heart failure, pulmonary hypertension in sickle cell disease, STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis, and on why the same drugs look different; a review article on glucocorticoid-induced bone disease; a Clinical Problem-Solving article on a sleeping giant; and Perspective ar ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - June 30, 2011 This summary covers the issue of June 30, 2011. Featured are articles on mortality after fluid bolus in African children with infection, mutations in myelodysplastic syndromes, vemurafenib in metastatic melanoma, ipilimumab plus dacarbazine for metastatic melanoma, and lessons from sickle cell disease in malaria; a review article on antitrypanosomal therapy for chronic Chagas’ disease; a case report of a man with diarrhea after a trip to the Caribbean; and Perspective articles on assess ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - June 23, 2011 This summary covers the issue of June 23, 2011. Featured are articles on exemestane in breast-cancer prevention; diet, lifestyle, and long-term weight gain; and telaprevir for previously untreated chronic HCV and for retreatment of HCV infection; review articles on chronic hepatitis C infection and on n–3 fatty acids in cardiovascular disease; a case report of a Haitian boy with vomiting and diarrhea; and Perspective articles on front-of-package nutrition labeling, on the banishment of ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - June 16, 2011 This summary covers the issue of June 16, 2011. Featured are articles on intussusception and benefits of rotavirus vaccination, meningococcal conjugate vaccine in Africans, BRAF mutations in hairy-cell leukemia, vaccine-derived poliomyelitis 12 years after infection, insurance and children’s access to specialty care, and elastogenesis in the vaginal wall and pelvic-organ prolapse; a review article on the health risks of nuclear accidents; a case report of an HIV-positive woman with head ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - June 9, 2011 This summary covers the issue of June 9, 2011. Featured are articles on transcatheter aortic-valve replacement, outcomes of hepatitis C treatment by PCPs, IUD insertion after uterine aspiration, a mutation in acrodysostosis and hormone resistance; review articles on mild cognitive impairment and on sirtuins, aging, and medicine; a case report of a woman with a breast mass and skin changes; and Perspective articles on menthol cigarettes and public health, on shifts in global health funding ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - June 2, 2011 This summary covers the issue of June 2, 2011. Featured are articles on blast-related traumatic brain injury in U.S. military, membranous nephropathy due to bovine serum albumin, saliva PCR assay for CMV screening in newborns, interleukin-2 plus gp100 peptide vaccine in melanoma, hospital volume and operative mortality, and the provenance of pluripotent stem cells; a review article on IV thrombolytic therapy for acute ischemic stroke; a Clinical Problem-Solving article describing a recurr ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - May 26, 2011 This summary covers the issue of May 26, 2011. Featured are articles on androgen deprivation in prostate cancer, bronchoconstriction and airway remodeling in asthma, bacterial meningitis in the United States, treadmill rehabilitation after stroke, and cutting the cost of oncology care; a review article on borderline personality disorder; a case report of a man with recurrent prostate cancer; and Perspective articles on the $640 billion question, on how Staphylococcus aureus adapts to its ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - May 19, 2011 This summary covers the issue of May 19, 2011. Featured are articles on ranibizumab or bevacizumab for age-related macular degeneration; alemtuzumab induction in renal transplantation; selenium and the course of mild Graves’ orbitopathy; and fish, fatty acid metabolism, and retinopathy; review articles on genomics and the eye and on acute HIV-1 infection; a case report of a woman with headache, fatigue, and vaginal discharge; and Perspective articles on the Palliative Care Informat ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - May 12, 2011 This summary covers the issue of May 12, 2011. Featured are articles on evidence of human lung stem cells, pneumatic dilation vs. laparoscopic Heller's myotomy for idiopathic achalasia, therapy for metastatic pancreatic cancer, anterior colporrhaphy vs. transvaginal mesh for pelvic-organ prolapse, and hemoglobin Toms River; a review article on the tumor lysis syndrome; a case report of a woman with asymmetric sensory loss and paresthesias; and Perspective articles on electroconvulsive the ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - May 5, 2011 This summary covers the issue of May 5, 2011. Featured are articles on leukotriene-receptor antagonists in asthma-controller therapy, radical prostatectomy vs. watchful waiting, stents vs. bypass surgery in left main coronary artery disease, and bisphosphonate and atypical fractures of the femoral shaft; review articles on sentinel-lymph-node biopsy for cutaneous melanoma and on whether clotting factors accelerate atherosclerosis; a Clinical Problem-Solving article describing a sweet sour ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - April 28, 2011 This summary covers the issue of April 28, 2011. Featured are articles on efficacy and safety of sirolimus in lymphangioleiomyomatosis, coronary-artery bypass surgery in left ventricular dysfunction, myocardial viability and survival in ischemic LV dysfunction, probable zoonotic leprosy in the southern U.S.; review articles on vertebral fractures and on inherited cardiomyopathies; a case report of a man with adenocarcinoma of the rectum; and Perspective articles on Medicaid at a crossroad ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - April 21, 2011 This summary covers the issue of April 21, 2011. Featured are articles on decompressive craniectomy in traumatic brain injury, a common polymorphism and pulmonary fibrosis, systemic PRO051 in Duchenne's muscular dystrophy, febrile thrombocytopenia and a novel bunyavirus in China, dissemination of Neisseria meningitidis, and new directions in medical liability reform; a review article on ciliopathies; a case report of a boy with acute liver failure; and Perspective articles on litigation a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - April 14, 2011 This summary covers the issue of April 14, 2011. Featured are articles on percutaneous repair of mitral regurgitation, reducing transmission of resistant bacteria in ICUs, a Veterans Affairs initiative to prevent MRSA infections, and normothermic ex vivo lung perfusion in transplantation; a review article on latent TB infection in the United States; a case report of a man with SLE and heart failure; and Perspective articles on vitamin D and prevention of cancer, on defining safe use of a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - April 7, 2011 This summary covers the issue of April 7, 2011. Featured are articles on functional disability 5 years after the acute respiratory distress syndrome, dalteparin vs. heparin in critically ill patients, adolescent BMI trajectory and risk of disease, an inactivated cell-culture vaccine for yellow fever, and the English NHS embarks on health care reforms; a review article on the Gulf Oil spill; a Clinical Problem-Solving article describing a man with abdominal distention and discomfort; and P ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - March 31, 2011 This summary covers the issue of March 31, 2011. Featured are articles on boceprevir for untreated chronic HCV infection, boceprevir for treatment-resistant chronic HCV infection, weight loss and exercise in obese elderly, growth hormone and estrogen in Turner's syndrome, and quality of care and litigation in nursing homes; a review article on care of transsexual persons; a case report of a woman with fever, confusion, liver failure, anemia, and thrombocytopenia; and Perspective articles ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - March 24, 2011 This summary covers the issue of March 24, 2011. Featured are articles on tiotropium vs. salmeterol for COPD exacerbations, pioglitazone for prevention of diabetes in impaired glucose tolerance, mercury and risk of cardiovascular disease, carbamazepine-induced toxic effects and HLA-B*1502 screening, carbamazepine-induced hypersensitivity in Europeans, subspecialization in internal medicine, and maternal response to in utero stem-cell transplantation; a review article on drugs, genes, and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - March 17, 2011 This summary covers the issue of March 17, 2011. Featured are articles on prenatal vs. postnatal repair of myelomeningocele, omalizumab for asthma in inner-city children, quality of life after PCI with drug-eluting stents or CABG, cytarabine dose for acute myeloid leukemia, and nurse staffing and inpatient hospital mortality; a review article on multiple myeloma; a case report of a woman with seizures and cognitive decline; and Perspective articles on the development of novel combination ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - March 10, 2011 This summary covers the issue of March 10, 2011. Featured are articles on lung volumes and emphysema in smokers, delay or prevention of microalbuminuria in type 2 diabetes, salmonella Saintpaul and raw produce, irbesartan in atrial fibrillation, a mutation and limb-girdle muscular dystrophy, and prodding progesterone action in pregnancy; a review article on non-small-cell lung cancer therapy with erlotinib or gefitinib; a case report of a man with upper respiratory symptoms and low oxygen ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - March 3, 2011 This summary covers the issue of March 3, 2011. Featured are articles on diuretic strategies in heart failure; apixaban in patients with atrial fibrillation; intensive glucose lowering and cardiovascular outcomes; diabetes, fasting glucose, and risk of death; risperidone in unstable schizophrenia; and the ClinicalTrials.gov results database; a review article on deep-vein thrombosis of the upper extremities; a Clinical Problem-Solving article on a woman with intermittent confusion; and Per ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - February 24, 2011 This summary covers the issue of February 24, 2011. Featured are articles on environmental microorganisms and childhood asthma, heterogeneity of hemoglobin H disease, BMI and risk of death in Asians, whole-genome sequencing and social-network analysis of a tuberculosis outbreak, perilipin deficiency and lipodystrophy, and melanoma and resistance to BRAF Inhibitor; a review article on point-of-care ultrasonography; a case report of a man with dyspnea, weakness, and diaphoresis; and Perspec ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - February 17, 2011 This summary covers the issue of February 17, 2011. Featured are articles on bevacizumab for stage 3+ retinopathy of prematurity, risk alleles in idiopathic membranous nephropathy, NFKBIA deletions in glioblastomas, safety of influenza A (H1N1) vaccine in China; review articles on streptococcal pharyngitis and on hypoxia and inflammation; a case report of a man with hematuria after therapy for prostate cancer; and Perspective articles on Medicare and end-stage renal disease and on health ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - February 10, 2011 This summary covers the issue of February 10, 2011. Featured are articles on sunitinib for pancreatic neuroendocrine tumors, everolimus in functional neuroendocrine tumors, consumer genomewide risk profiling, public-sector research and discovery of drugs and vaccines, biomedical research and health advances, and gene therapy of a leukodystrophy; a review article on radioiodine therapy for hyperthyroidism; a case report of a boy with back pain and hypercalcemia; and Perspective articles on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - February 3, 2011 This summary covers the issue of February 3, 2011. Featured are articles on quadrivalent HPV vaccine vs. HPV infection in males, occult metastases in breast cancer, fidaxomicin vs. vancomycin for Clostridium difficile, NT5E mutations and arterial calcifications, and equipoise and the dilemma of randomized clinical trials; review articles on gout and on myocardial infarction due to PCI; a Clinical Problem-Solving article on avoiding a rash diagnosis; and Perspective articles on the benefit ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - January 27, 2011 This summary covers the issue of January 27, 2011. Featured are articles on the prevention of catheter malfunction with rt-PA, cardiac arrest in public vs. at home, peginterferon plus adefovir vs. either alone for hepatitis delta virus, induced first-trimester abortion and mental disorder, and a measure of the red cell; review articles on the genome and cancer and on chronic thromboembolic pulmonary hypertension; a case report of a woman with a mass in the liver; and Perspective articles ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - January 20, 2011 This summary covers the issue of January 20, 2011. Featured are articles on PARP inhibition in triple-negative breast cancer, genetic basis for functional hypothalamic amenorrhea, a prospective study of coronary atherosclerosis, and nucleic acid testing for HBV in blood; review articles on vitamin D insufficiency and on necrotizing enterocolitis; a case report of a woman with shock after treatment of a furuncle; and Perspective articles on broadening the scope of nursing practice, on nurs ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - January 13, 2011 This summary covers the issue of January 13, 2011. Featured are articles on the treatment of acute otitis media in young children, cholesterol efflux capacity and atherosclerosis, a genetic variant of the scavenger receptor BI, rapidly evolving physician-payment policy, and calling the cardiomyocyte; a review article on iron-chelating therapy for transfusional iron overload; a case report of a man with fever, bacteremia, and a left atrial mass; and Perspective articles on the struggle aga ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - January 6, 2011 This summary covers the issue of January 6, 2011. Featured are articles on eplerenone in systolic heart failure with mild symptoms, rifaximin for patients with IBS without constipation, genomic analysis of Vibrio cholerae strains from Haiti, AIP mutation in a giant and in contemporary families; review articles on bipolar disorder and on genetic defects of pattern-recognition receptors; a Clinical Problem-Solving article describing a crazy cause of dyspnea; and Perspective articles on heal ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 30, 2010 This summary covers the issue of December 30, 2010. Featured are articles on preexposure prophylaxis for HIV; residual NADPH oxidase and chronic granulomatous disease; collaborative care for depression and chronic illnesses; parapoxvirus infection in deer hunters; homozygous BUB1B mutation and GI neoplasia; and rosiglitazone, PPAR-gamma, and type 2 diabetes; a review article on general anesthesia, sleep, and coma; a case report of a woman with chest pain during an airplane flight; and Per ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 23, 2010 This summary covers the issue of December 23, 2010. Featured are articles on apixaban for thromboprophylaxis after hip replacement, rivaroxaban for venous thromboembolism, imatinib plus peginterferon alfa-2a in chronic myeloid leukemia, long-term mortality in childhood-onset epilepsy, and measuring hospital-wide mortality; a review article on glycemic control in the ICU; a case report of a woman with nausea, jaundice, and pruritus; and Perspective articles on value in health care, on putt ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 16, 2010 This summary covers the issue of December 16, 2010. Featured are articles on cardiac-resynchronization therapy for heart failure, teriparatide and osseous regeneration, anacetrapib and coronary heart disease, safety and effectiveness of H1N1 vaccine in Beijing, DNA methyltransferase and acute myeloid leukemia, and sorting out cholesterol and coronary artery disease; a review article on nanomedicine; a case report of a girl with an enlarging neck mass; and Perspective articles on NDM-1, on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 9, 2010 This summary covers the issue of December 9, 2010. Featured are articles on frequency of hemodialysis, telemonitoring in heart failure, drug-eluting vs. bare-metal stents, neonatal abstinence syndrome after methadone or buprenorphine exposure; review articles on Tourette's syndrome and on genomics, type 2 diabetes, and obesity; a case report of a girl with confusion, anemia, and thrombocytopenia; and Perspective articles on the future of health care reform, on a national cholera vaccine s ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - December 2, 2010 This summary covers the issue of December 2, 2010. Featured are articles on uveal melanoma; docetaxel for high-risk, node-negative breast cancer; BMI and mortality among 1.46 million white adults; exome sequencing and familial combined hypolipidemia; innovation, regulation, and the FDA; and modulating fetal hemoglobin; a review article on airway mucus function and dysfunction; a Clinical Problem-Solving article describing a man with nausea, vomiting, nocturia, and polyuria; and Perspectiv ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 25, 2010 This summary covers the issue of November 25, 2010. Featured are articles on mortality after stem-cell transplantation; protein, glycemic index, and weight-loss maintenance; proton-pump inhibitors and the risk of birth defects; temporal trends in patient harm; and eponyms for the astute auscultician; a review article on retinal-vein occlusion; a case report of a woman with pain and loss of hearing; and Perspective articles on geographic variation in the use of rosiglitazone, on Medicaid e ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 18, 2010 This summary covers the issue of November 18, 2010. Featured are articles on the potentiation of CFTR in cystic fibrosis, kidney transplantation in patients with HIV, n-3 fatty acids and cardiovascular events, medical malpractice liability and EHRs, and diabetic nephropathy and the podocyte; review articles on bisphosphonates for osteoporosis and on influenza vaccines for the future; a case report of a man with cough, hypoxemia, and rash; and Perspective articles on a flood of opioids and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 11, 2010 This summary covers the issue of November 11, 2010. Featured are articles on romiplostim in immune thrombocytopenia, diet in infancy and later autoimmunity, clopidogrel and omeprazole in coronary disease, stem-cell gene therapy for Wiskott–Aldrich syndrome, and effect of a surgical safety system on outcomes; a review article on triple-negative breast cancer; a case report of a woman with an incorrect operation on the left hand; and Perspective articles on the constitutionality of health ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - November 4, 2010 This summary covers the issue of November 4, 2010. Featured are articles on recombinant factor VII in clinical trials, everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis, brentuximab vedotin for relapsed CD30-positive cancers, reimbursement policy and androgen-deprivation therapy, market exclusivity and pharmaceutical innovation, and eating up alpha1-antitrypsin aggregates; a review article on hemodialysis; a Clinical Problem-Solving article describing bitter pills; ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 28, 2010 This summary covers the issue of October 28, 2010. Featured are articles on ALK inhibition in non-small-cell lung cancer, clopidogrel metabolism and clinical outcomes, tiotropium step-up therapy for uncontrolled asthma, crizotinib in ALK-rearranged inflammatory myoblastic tumors, and EML4-ALK mutations in lung cancer; a review article on recurrent miscarriage; a case report of a woman with blurred vision and renal failure; and Perspective articles on the midterm elections, on the resurrec ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 21, 2010 This summary covers the issue of October 21, 2010. Featured are articles on transcatheter aortic-valve implantation for stenosis, effect of home INR testing on clinical events, expression of the FSH receptor in tumor blood vessels, CHUK and the cocoon syndrome, and replacing the photoreceptor in retinitis pigmentosa; review articles on cardiac development and implications for heart disease and on ranibizumab therapy for neovascular age-related macular degeneration; a case report of a preg ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 14, 2010 This summary covers the issue of October 14, 2010. Featured are articles on antiretroviral therapy and maternal and infant nevirapine exposure, tanezumab, pain, and osteoarthritis, and ARID1A mutations in ovarian carcinomas; review articles on nausea and vomiting in pregnancy and on ancestry, genomics, and disease; a case report of a woman with fever after a cat bite; and Perspective articles on regulatory action on rosiglitazone by the FDA, on reviving the FDA, and on legislating against ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - October 7, 2010 This summary covers the issue of October 7, 2010. Featured are articles on pluripotent stem-cell models for long-QT syndrome, hypoglycemia and risk of vascular events and death, rolofylline in acute heart failure, dystrophin immunity in Duchenne's muscular dystrophy, and microflora, parasites, and immunity; review articles on profound deafness in childhood and on kidney allograft rejection; a Clinical Problem-Solving article describing a heavy heart; and Perspective articles on opportunit ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 30, 2010 This summary covers the issue of September 30, 2010. Featured are articles on a Syk inhibitor for rheumatoid arthritis, outcome after reduced chemotherapy for neuroblastoma, immunotherapy for neuroblastoma, timing of de novo mutagenesis, and placebo-controlled trials of fracture in osteoporosis; a review article on the risk of cardiovascular disease in patients with nonalcoholic fatty liver disease; a case report of a boy with a recurrent skin lesion; and Perspective articles on traumatic ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 23, 2010 This summary covers the issue of September 23, 2010. Featured are articles on the effect of screening on breast-cancer mortality in Norway, genetic susceptibility to asthma, fondaparinux for superficial-vein thrombosis, endobronchial valves for advanced emphysema, and a strategy for telephone care management; a review article on targeted temperature management for comatose survivors of cardiac arrest; a case report of a woman with fever and abdominal pain; and Perspective articles on movi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 16, 2010 This summary covers the issue of September 16, 2010. Featured are articles on neuromuscular blockers in early ARDS, JAK1 and JAK2 inhibition in myelofibrosis, susceptibility to exacerbation in COPD, smoke-free legislation and childhood asthma, and darbepoetin and kidney disease; a review article on idiopathic urgency urinary incontinence; a case report of a woman, 3 weeks post partum, with substernal chest pain; and Perspective articles on the safety of tiotropium, on preparing for a cons ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 9, 2010 This summary covers the issue of September 9, 2010. Featured are articles on rapid detection of TB and rifampin resistance, genes and Fuchs's corneal dystrophy, malignant stem cells in myelodysplastic syndrome, the gentamicin-collagen sponge in colorectal surgery, and lessons from the mammography wars; a review article on MDR-TB -- critical steps for prevention and control; a case report of a woman with chronic anemia; and Perspective articles on screening student athletes for sickle cell t ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - September 2, 2010 This summary covers the issue of September 2, 2010. Featured are articles on sibutramine and cardiovascular outcomes in overweight and obese subjects, intensive blood-pressure control in hypertensive chronic kidney disease, dose comparisons of clopidogrel and aspirin in acute coronary syndromes, chemotherapy or surgery in ovarian cancer, and disclosure of large-scale adverse events; a review article on calcium kidney stones; a Clinical Problem-Solving article on a woman originally from Ne ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - August 26, 2010 This summary covers the issue of August 26, 2010. Featured are articles on inhibition of mutated, activated BRAF in metastatic melanoma, sirolimus and kidney growth in autosomal dominant polycystic kidney disease, everolimus in patients with autosomal dominant polycystic kidney disease, underinsurance among children in the United States, and cancer and caprice; a review article on new therapeutic approaches to mendelian disorders; a case report of a man with loss of vision and a rash; and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 8. This summary covers the issue of August 12, 2010. Featured are articles on improved survival with ipilimumab in patients with metastatic melanoma, racial variation in medical outcomes among living kidney donors, early palliative care for patients with metastatic cancer, a randomized trial of tai chi for fibromyalgia, and HPV vaccination mandates; a review article on the emergency treatment of asthma; a case report of a woman with abdominal pain and shock; and Perspective articles on robot ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 7. This summary covers the issue of August 12, 2010. Featured are articles on early versus late initiation of dialysis, sildenafil for advanced idiopathic pulmonary fibrosis, bone marrow transplantation for recessive dystrophic epidermolysis bullosa, treatment intensity in Hodgkin's lymphoma, accountability measures to promote quality, and vascular dissection and sepsis; a review article on early-stage Hodgkin's lymphoma; a case report of a woman with a history of Hodgkin's lymphoma and sudde ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 6. This summary covers the issue of August 5, 2010. Featured are articles on the treatment of hereditary angioedema; suicide-related events in patients treated with antiepileptic drugs; myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy; and health reform, primary care, and graduate medical education; a review article on transverse myelitis; a Clinical Problem-Solving article on thinking inside the box; and Perspective articles on the "meaningful use" regulation for ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 5. This summary covers the issue of July 29, 2010. Featured are articles on sipuleucel-T immunotherapy for castration-resistant prostate cancer, CPR with chest compression alone or with rescue breathing, compression-only CPR or standard CPR in out-of-hospital cardiac arrest, a school-based intervention for diabetes risk reduction, and understanding severe dengue; a review article on acupuncture for chronic low back pain; a case report of a man with perinephric fluid collections and renal fail ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 5. This summary covers the issue of July 29, 2010. Featured are articles on sipuleucel-T immunotherapy for castration-resistant prostate cancer, CPR with chest compression alone or with rescue breathing, compression-only CPR or standard CPR in out-of-hospital cardiac arrest, a school-based intervention for diabetes risk reduction, and understanding severe dengue; a review article on acupuncture for chronic low back pain; a case report of a man with perinephric fluid collections and renal fail ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 4. This summary covers the issue of July 22, 2010. Featured are articles on sensor-augmented insulin-pump therapy in type 1 diabetes, prediction of lung cancer, treatment for acute ACL tears, molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis, and efficacy of gene therapy for X-linked severe combined immunodeficiency; a review article on functional hypothalamic amenorrhea; a case report of a woman with dementia and a seizure; and Perspective articles on the path to pe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 4. This summary covers the issue of July 22, 2010. Featured are articles on sensor-augmented insulin-pump therapy in type 1 diabetes, prediction of lung cancer, treatment for acute ACL tears, molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis, and efficacy of gene therapy for X-linked severe combined immunodeficiency; a review article on functional hypothalamic amenorrhea; a case report of a woman with dementia and a seizure; and Perspective articles on the path to pe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 4. This summary covers the issue of July 22, 2010. Featured are articles on sensor-augmented insulin-pump therapy in type 1 diabetes, prediction of lung cancer, treatment for acute ACL tears, molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis, and efficacy of gene therapy for X-linked severe combined immunodeficiency; a review article on functional hypothalamic amenorrhea; a case report of a woman with dementia and a seizure; and Perspective articles on the path to pe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 3. This summary covers the issue of July 15, 2010. Featured are articles on rituximab versus cyclophosphamide for ANCA-associated vasculitis, retinopathy progression in type 2 diabetes, lorcaserin for weight management, early versus standard antiretroviral therapy for HIV-infected adults in Haiti, and metabolic disorders and fat transport; a review article on acute pulmonary embolism; a case report of a request for oocyte retrieval from a woman with anoxic brain injury; and Perspective articl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 3. This summary covers the issue of July 15, 2010. Featured are articles on rituximab versus cyclophosphamide for ANCA-associated vasculitis, retinopathy progression in type 2 diabetes, lorcaserin for weight management, early versus standard antiretroviral therapy for HIV-infected adults in Haiti, and metabolic disorders and fat transport; a review article on acute pulmonary embolism; a case report of a request for oocyte retrieval from a woman with anoxic brain injury; and Perspective articl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 3. This summary covers the issue of July 15, 2010. Featured are articles on rituximab versus cyclophosphamide for ANCA-associated vasculitis, retinopathy progression in type 2 diabetes, lorcaserin for weight management, early versus standard antiretroviral therapy for HIV-infected adults in Haiti, and metabolic disorders and fat transport; a review article on acute pulmonary embolism; a case report of a request for oocyte retrieval from a woman with anoxic brain injury; and Perspective articl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 2. This summary covers the issue of July 8, 2010. Featured are articles on adverse events with testosterone administration, late-onset hypogonadism in middle-aged and elderly men, zotarolimus-eluting vs. everolimus-eluting stents, restoring vision after corneal damage, and new recommendations on duty hours from the ACGME task force; review articles on mitral regurgitation due to degenerative mitral-valve disease and on genomewide association studies and assessment of the risk of disease; a ca ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 2. This summary covers the issue of July 8, 2010. Featured are articles on adverse events with testosterone administration, late-onset hypogonadism in middle-aged and elderly men, zotarolimus-eluting vs. everolimus-eluting stents, restoring vision after corneal damage, and new recommendations on duty hours from the ACGME task force; review articles on mitral regurgitation due to degenerative mitral-valve disease and on genomewide association studies and assessment of the risk of disease; a ca ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 2. This summary covers the issue of July 8, 2010. Featured are articles on adverse events with testosterone administration, late-onset hypogonadism in middle-aged and elderly men, zotarolimus-eluting vs. everolimus-eluting stents, restoring vision after corneal damage, and new recommendations on duty hours from the ACGME task force; review articles on mitral regurgitation due to degenerative mitral-valve disease and on genomewide association studies and assessment of the risk of disease; a ca ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 1. This summary covers the issue of July 1, 2010. Featured are articles on stenting vs. endarterectomy for carotid-artery stenosis; HPV and oropharyngeal cancer; an entirely subcutaneous implantable cardioverter-defibrillator; regional variations in diagnostic practices; geographic differences in Medicare spending; and immunosuppression, HIV, and sepsis; a review article on triptan therapy in migraine; a Clinical Problem-Solving article describing a rash hypothesis; and Perspective articles o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 363, No. 1. This summary covers the issue of July 1, 2010. Featured are articles on stenting vs. endarterectomy for carotid-artery stenosis; HPV and oropharyngeal cancer; an entirely subcutaneous implantable cardioverter-defibrillator; regional variations in diagnostic practices; geographic differences in Medicare spending; and immunosuppression, HIV, and sepsis; a review article on triptan therapy in migraine; a Clinical Problem-Solving article describing a rash hypothesis; and Perspective articles o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 25. This summary covers the issue of June 24, 2010. Featured are articles on fractional doses of inactivated poliovirus vaccine in Oman, circulating vaccine-derived poliovirus in Nigeria, early TIPS in cirrhosis with variceal bleeding, and gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR; review articles on endometriosis and on genetic disorders of renal phosphate transport; a case report of a man with adenocarcinoma of the cecum; and Perspective articles on transpare ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 24. This summary covers the issue of June 17, 2010. Featured are articles on nilotinib vs. imatinib for newly diagnosed CML, dasatinib vs. imatinib in newly diagnosed chronic-phase CML, maternal or infant antiretroviral drugs to reduce HIV-1 transmission, antiretroviral regimens in pregnancy and breast-feeding in Botswana, regulation of smoking in public housing, and Wnt signaling and acute myeloid leukemia; a review article on nicotine addiction; a case report of a boy with elevated HIV RNA l ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 23. This summary covers the issue of June 10, 2010. Featured are articles on population trends in the incidence and outcomes of acute myocardial infarction, oseltamivir ring prophylaxis for containment of 2009 H1N1 influenza outbreaks, comparative epidemiology of pandemic and seasonal influenza A in households, and valproic acid in pregnancy and congenital malformations; review articles on early Alzheimer's disease and on recent advances in neuroblastoma; a case report of a woman with flexion ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 22. This summary covers the issue of June 3, 2010. Featured are articles on longer therapy, amenorrhea, and survival in early breast cancer; retropubic versus transobturator midurethral slings for stress incontinence; deep-brain stimulation for Parkinson’s disease; genetic susceptibility to infectious disease; standard of care in emergencies; and the mitochondrion in inflammation; a review article on dietary therapy in hypertension; a Clinical Problem-Solving article describing a woman w ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 21. This summary covers the issue of May 27, 2010. Featured are articles on target ranges of oxygen saturation in extremely preterm infants, early CPAP versus surfactant in extremely preterm infants, and a comparison of shunt types in the Norwood procedure for single-ventricle lesions; review articles on infectious mononucleosis and on genomic medicine -- an updated primer; a case report of a man with cough and pain in the left shoulder; and Perspective articles on pandemic vaccines -- the leg ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 20. This summary covers the issue of May 20, 2010. Featured are articles on endovascular versus open repair of abdominal aortic aneurysm, endovascular repair of aortic aneurysm in patients physically ineligible for open repair, long-term outcome of repair of abdominal aortic aneurysm, gene-expression profiling after cardiac transplantation, L-histidine decarboxylase and Tourette's syndrome, and sperm and the proton channel; a review article on susceptibility pathways in Fanconi's anemia and br ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 18. This summary covers the issue of May 13, 2010. Featured are articles on bisphosphonates and fractures of the subtrochanteric or diaphyseal femur, robot-assisted therapy for upper-limb impairment after stroke, maternal vitamin A supplementation and lung function in offspring, quality indicators for colonoscopy and the risk of interval cancer, and whistle-blowers' experiences in fraud litigation against pharmaceutical companies; a review article on hospital-acquired infections due to gram-ne ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 18. This summary covers the issue of May 6, 2010. Featured are articles on everolimus-eluting versus paclitaxel-eluting stents, pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis, generalized vitiligo and tyrosinase, effect of bar-code technology on the safety of medication administration, information technology and global surveillance of H1N1, and susceptibility to coronary artery disease; a review article on clinical aspects of pandemic 2009 influenza A (H1N1) virus infecti ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 17. This summary covers the issue of April 29, 2010. Featured are articles on the effects of combination lipid therapy in type 2 diabetes mellitus, effects of intensive blood-pressure control in type 2 diabetes mellitus, aspirin plus heparin or aspirin alone in women with recurrent miscarriage, and a snapshot from one primary care practice; review articles on Helicobacter pylori infection and on pancreatic cancer; a case report of a girl with watery diarrhea and poor weight gain; and Perspecti ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 16. This summary covers the issue of April 22, 2010. Featured are articles on nateglinide and progression of impaired glucose tolerance, effect of valsartan on the incidence of diabetes and cardiovascular events, a step-up approach or open necrosectomy in necrotizing pancreatitis, and RFX6 and the pancreatic beta cell; review articles on epidural analgesia for labor and delivery and on the recent evolution of vaccines against Neisseria meningitidis infection; a case report of a man with progre ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 15. This summary covers the issue of April 15, 2010. Featured are articles on lenient vs. strict rate control for atrial fibrillation, dual antiplatelet therapy and drug-eluting stents, therapy for Crohn's disease, and alglucosidase alfa in late-onset Pompe's disease; review articles on outpatient management of severe COPD and on aggressive lymphomas; a case report of a woman with lethargy, confusion, and abnormalities on brain imaging; and Perspective articles on malpractice reform, on the po ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 14. This summary covers the issue of April 8, 2010. Featured are articles on lung function in rescue workers at the World Trade Center after 7 years, cisplatin plus gemcitabine versus gemcitabine for biliary tract cancer, vitamins C and E to prevent complications of pregnancy-associated hypertension, telaprevir for previously treated chronic HCV infection, an evaluation of a redesign initiative in an internal-medicine residency, and a principle of system balance for drug interactions; a review ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 13. This summary covers the issue of April 1, 2010. Featured are articles on trajectories of disability in the last year of life, whole-genome sequencing and causes of disease, effect of dutasteride on the risk of prostate cancer, glycogenin-1 deficiency and inactivated priming of glycogen synthesis, and advance directives and decision making before death; a review article on prolactinomas; a Clinical Problem-Solving article describing more than meets the ear; and Perspective articles on moder ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 12. This summary covers the issue of March 25, 2010. Featured are articles on rifaximin treatment in hepatic encephalopathy, apolipoprotein C3 gene variants in nonalcoholic fatty liver disease, prevalence of diabetes among men and women in China, a loss-of-function mutation in NaPi-IIa and renal Fanconi's syndrome, hospital volume and 30-day mortality for three common medical conditions, and isocitrate dehydrogenase and glioma; a review article on stereotactic radiosurgery for the management o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 11. This summary covers the issue of March 18, 2010. Featured are articles on step-up therapy for children with uncontrolled asthma, performance of common genetic variants in breast-cancer risk models, nationwide public-access defibrillation in Japan, corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells, and physician cost profiling; a review article on vertebral osteomyelitis; a case report of a woman with hypercalcemia and a pelvic mass; and Perspective articles on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 11. This summary covers the issue of March 18, 2010. Featured are articles on step-up therapy for children with uncontrolled asthma, performance of common genetic variants in breast-cancer risk models, nationwide public-access defibrillation in Japan, corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells, and physician cost profiling; a review article on vertebral osteomyelitis; a case report of a woman with hypercalcemia and a pelvic mass; and Perspective articles on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 10. This summary covers the issue of March 11, 2010. Featured are articles on tumor-associated macrophages and survival in classic Hodgkin's lymphoma, low diagnostic yield of coronary angiography, oral ivermectin versus malathion lotion for difficult-to-treat head lice, use of the thyroid hormone analogue eprotirome in statin-treated dyslipidemia, and ameliorating amyotrophic lateral sclerosis; a review article on commotio cordis; a case report of a man with peripheral neuropathy and ascites; ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 9. This summary covers the issue of March 4, 2010. Featured are articles on dopamine vs. norepinephrine for shock; ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy; glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults; pneumococcal conjugate vaccine in HIV-infected adults; and the collection of data on patients' race and ethnic group; a review article on the management of varices and variceal hemorrhage in cirrhosis; a Clinical Problem-Solving ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 8. This summary covers the issue of February 25, 2010. Featured are articles on genetic associations with stuttering, lasofoxifene and osteoporosis, timing of initiation of antiretroviral drugs during tuberculosis therapy, an algorithm for tuberculosis screening and diagnosis in people with HIV, and wrestling with BRCA1; review articles on permethrin and ivermectin for scabies and on Graves' ophthalmopathy; a case report of a man with a lesion on the tongue; and Perspective articles on confli ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 7. This summary covers the issue of February 18, 2010. Featured are articles on the willful modulation of brain activity in disorders of consciousness, projected effect of dietary salt reductions on future cardiovascular disease, dose of prophylactic platelet transfusions and prevention of hemorrhage, and newborn-care training and perinatal mortality in developing countries; a review article on the small renal mass; a case report of a man with HIV infection, proteinuria, and edema; and Perspe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 6. This summary covers the issue of February 11, 2010. Featured are articles on childhood obesity, other cardiovascular risk factors, and premature death; stent graft versus balloon angioplasty for failing dialysis-access grafts; single-dose liposomal amphotericin B for visceral leishmaniasis in India; long-term results of hypofractionated radiation therapy for breast cancer; lack of cyclophilin B in osteogenesis imperfecta; and innate immunity and HIV; a review article on the enigma of spont ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 5. This summary covers the issue of February 4, 2010. Featured are articles on a placebo-controlled study of oral fingolimod in relapsing multiple sclerosis, oral fingolimod or intramuscular interferon for relapsing multiple sclerosis, cladribine or placebo for relapsing multiple sclerosis, acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2, and comparative effectiveness and health care spending; a review article on jet lag; a Clinical Problem-Solving article descr ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 4. This summary covers the issue of January 28, 2010. Featured are articles on rotavirus vaccine and severe gastroenteritis in African infants, effect of rotavirus vaccine on death from childhood diarrhea in Mexico, outcomes after internal versus external tocodynamometry for monitoring labor, vaccine-acquired rotavirus in infants with severe combined immunodeficiency, increased ambulatory care copayments and hospitalizations among the elderly, and insight into insulin secretion; a review artic ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 3. This summary covers the issue of January 21, 2010. Featured are articles on treatment with monoclonal antibodies against Clostridium difficile infection, skeletal dysplasia and the Golgi apparatus, and left ventricular filling in emphysema and airflow obstruction; review articles on systolic heart failure and on Williams-Beuren syndrome; a case report of a man with abdominal and flank pain; and Perspective articles on erythropoiesis-stimulating agents and on accelerating the use of electro ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 2. This summary covers the issue of January 14, 2010. Featured are articles on the use of mental health services among U.S. Army wives, morphine use after combat injury in Iraq and PTSD, ustekinumab versus etanercept for moderate-to-severe psoriasis, preoperative biliary drainage for pancreatic cancer, tracheal allotransplantation after withdrawal of immunosuppressive therapy, and progenitor cells of prostate cancer; a review article on nosocomial bacterial meningitis; a case report of a man ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 362, No. 1. This summary covers the issue of January 7, 2010. Featured are articles on preventing surgical-site infections in nasal carriers of S. aureus, chlorhexidine-alcohol for surgical-site antisepsis, severe 2009 H1N1 influenza in pregnant and postpartum women, variants of DENND1B and asthma in children, and pediatric hospitalizations associated with 2009 H1N1 influenza in Argentina; a review article on stage IV chronic kidney disease; a Clinical Problem-Solving article describing painful purple ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 27. This summary covers the issue of December 31, 2009. Featured are articles on MMP12, lung function, and COPD in high-risk populations; genetic susceptibility to infection by Mycobacterium leprae; household transmission of 2009 H1N1 influenza; outbreak of 2009 H1N1 influenza at a New York City School; public reporting of discharge planning and rates of readmissions; and molecular control of age-related diseases; a review article on activated protein C for sepsis; a case report of a boy with ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 26. This summary covers the issue of December 24, 2009. Featured are articles on the clinical features of the initial cases of 2009 H1N1 virus infection in China, genetic variants associated with Lp(a) lipoprotein level and coronary disease, long-term outcome associated with early repolarization, and a sensitive troponin T assay in stable coronary artery disease; a review article on Barrett's esophagus; a case report of a man with fever and respiratory failure; and Perspective articles on gett ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 25. This summary covers the issue of December 17, 2009. Featured are articles on three trials of 2009 H1N1 vaccines, ferric carboxymaltose in patients with heart failure and iron deficiency, limiting industry's influence on CME, and gene therapy for color blindness; a review article on the molecular basis of colorectal cancer; a case report of a pregnant woman with acute cardiac failure; and Perspective articles on a Republican view of health care reform, on the consequences of "no" to health ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 24. This summary covers the issue of December 10, 2009. Featured are articles on allogeneic hematopoietic stem-cell transplantation for sickle cell disease, platelet inhibition with cangrelor in patients undergoing PCI, and dabigatran vs. warfarin for acute venous thromboembolism; a review article on telomere diseases; a case report of a boy with paroxysmal headaches and visual changes; and Perspective articles on two essential elements of delivery-system reform; on the Supreme Court, process p ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 23. This summary covers the issue of December 3, 2009. Featured are articles on a vaccine regimen to prevent HIV-1 infection in Thailand, management of lung nodules detected by volume CT scanning, abacavir-lamivudine versus tenofovir-emtricitabine for initial HIV-1 therapy, continuous-flow left ventricular assist for advanced heart failure, forecasting the effects of obesity and smoking on U.S. life expectancy, and a look at the low-carbohydrate diet; a review article on mitral-valve repair fo ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 22. This summary covers the issue of November 26, 2009. Featured are articles on niacin or ezetimibe and carotid intima-media thickness; biventricular pacing in patients with bradycardia and normal ejection fraction; a novel antibody associated with autoimmune pancreatitis; and rituximab, B-lymphocyte depletion, and preservation of beta-cell function; a review article on diuretics for hypertension; a case report of a woman with chronic renal failure, leg swelling, and skin changes; and Perspec ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 21. This summary covers the issue of November 19, 2009. Featured are articles on a trial of darbepoetin alfa to reduce cardiovascular events, inflammatory bowel disease and interleukin-10 signaling, combined immunodeficiency associated with DOCK8 mutations, a novel protective prion protein variant and kuru exposure, and pancreatic cancer and the hedgehog pathway; a review article on inflammatory bowel disease; a case report of a man with cough, hoarseness, and abnormalities on chest imaging; a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 20. This summary covers the issue of November 12, 2009. Featured are articles on critical care services and 2009 H1N1 influenza in Australia and New Zealand; hospitalized patients with 2009 H1N1 influenza in the United States, April-June; cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus, revascularization versus medical therapy for renal-artery stenosis, and outcome reporting in industry-sponsored trials of gabapentin for off-label use; a review article on renal-arte ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 19. This summary covers the issue of November 5, 2009. Featured are articles on on-pump versus off-pump CABG, vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia, a peptide-based erythropoietin-receptor agonist for pure red-cell aplasia, testosterone and spermatogenesis, and figuring out ferroportin; review articles on phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension and on myelodysplastic syndromes; a Clinical Problem-Solving article describing ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 18. This summary covers the issue of October 29, 2009. Featured are articles on the association between susceptibility to fungal infections and a mutation in CARD9, three-year efficacy of complex insulin regimens in type 2 diabetes, antibiotic prophylaxis and recurrent urinary tract infection in children, and human dectin-1 deficiency and mucocutaneous fungal infections; review articles on postexposure prophylaxis for HIV infection and on norovirus gastroenteritis; a case report of a man with ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 17. This summary covers the issue of October 22, 2009. Featured are articles on intensity of continuous renal-replacement therapy in critically ill patients, strict blood-pressure control and progression of renal failure in children, glucocerebrosidase mutations in Parkinson’s disease, cisplatin versus cisplatin plus doxorubicin for standard-risk hepatoblastoma, X-linked thrombophilia with a mutant factor IX, and probing prostate cancer; a review article on atypical hemolytic–uremic ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 16. This summary covers the issue of October 15, 2009. Featured are articles on the clinical course of advanced dementia, functional status of elderly adults before and after initiation of dialysis, interleukin-2 therapy in patients with HIV infection, and the benefits of taxing sugar-sweetened beverages; review articles on bacterial diarrhea and on cell death; a case report of a man with progressive dyspnea; and Perspective articles on controlling expenditures by improving care for patients n ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 15. This summary covers the issue of October 8, 2009. Featured are articles on defibrillator implantation early after myocardial infarction, microRNA expression, survival, and response to interferon in liver cancer, doxycycline for Mansonella perstans infection, osteoporosis associated with neutralizing autoantibodies against osteoprotegerin, accuracy of conflict-of-interest statements, and gray-matter injury in multiple sclerosis; a review article on DNA damage, aging, and cancer; a case repo ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 14. This summary covers the issue of October 1, 2009. Featured are articles on cardiac-resynchronization therapy for the prevention of heart-failure events, a multicenter, randomized trial of treatment for mild gestational diabetes, moderate hypothermia for perinatal asphyxial encephalopathy, recurrence of bile salt export pump deficiency after liver transplantation, variation in hospital mortality associated with inpatient surgery, and balancing "no blame" with accountability in patient safet ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 13. This summary covers the issue of September 24, 2009. Featured are articles on daunorubicin for acute myeloid leukemia in older patients, anthracycline dose intensification in AML, comparative efficacy of inactivated and live attenuated influenza vaccines, a double-blind, delayed-start trial of rasagiline in Parkinson's disease, the delayed-start study design, interferon-alpha; and the treatment of leukemia; a review article on renal failure in cirrhosis; a case report of a man with recurre ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 12. This summary covers the issue of September 17, 2009. Featured are articles on dabigatran versus warfarin in patients with atrial fibrillation, sex hormone-binding globulin and risk of type 2 diabetes in women and men, inhibition of the hedgehog pathway in advanced basal-cell carcinoma, treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449, and Congress, the FDA, and drug-regulation preemption; a review article on screening for colorectal cancer; a case report of a man with w ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 11. This summary covers the issue of September 10, 2009. Featured are articles on ticagrelor versus clopidogrel in patients with acute coronary syndromes, recurring mutations in acute myeloid leukemia, asymptomatic reactivation of JC virus in patients treated with natalizumab, treatment of progressive multifocal leukoencephalopathy associated with natalizumab, PML after natalizumab monotherapy, and understanding abdominal aortic aneurysm; a review article on parenteral nutrition in the critica ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 10. This summary covers the issue of September 3, 2009. Featured are articles on gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma, screening for epidermal growth factor receptor mutations in lung cancer, injectable collagenase clostridium histolyticum for Dupuytren's contracture, and fluvastatin in patients undergoing vascular surgery; review articles on coronary calcium screening for cardiovascular prevention and on intestinal transplantation; a Clinical Problem-Solving article ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 9. This summary covers the issue of August 27, 2009. Featured are articles on exposure to low-dose ionizing radiation from medical imaging procedures, early diagnosis of myocardial infarction with sensitive cardiac troponin assays, sensitive troponin I assay in early diagnosis of acute myocardial infarction, the hypertension paradox, disclosure of financial relationships to participants in clinical research, and finding the weakness in cancer; a review article on interleukin-17 and type 17 he ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 8. This summary covers the issue of August 20, 2009. Featured are articles on denosumab in men receiving androgen-deprivation therapy for prostate cancer, denosumab for prevention of fractures in postmenopausal women with osteoporosis, letrozole therapy alone or in sequence with tamoxifen in women with breast cancer, and diacetylmorphine versus methadone for the treatment of opioid addiction; review articles on infection associated with prosthetic joints and on the sudden infant death syndrom ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 6. This summary covers the issue of August 6, 2009. Featured are articles on vertebroplasty for osteoporotic vertebral fractures, peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection, apixaban or enoxaparin for thromboprophylaxis after knee replacement, and health care reform and more freedom, and responsibility, for physicians; a review article on neurologic prognosis after cardiac arrest; a Clinical Problem-Solving article describing a hard diagnosis; and Pe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 5. This summary covers the issue of July 30, 2009. Featured are articles on perioperative safety in the longitudinal assessment of bariatric surgery, artemisinin-resistant Plasmodium falciparum malaria, protection against a malaria challenge by sporozoite inoculation, loss of mismatched HLA in leukemia after stem-cell transplantation, variant AGC1 and hypomyelination, and plasmodium and the platelet; a review article on psoriasis; a case report of a woman with painful swelling of the neck; an ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 4. This summary covers the issue of July 23, 2009. Featured are articles on a cluster-randomized effectiveness trial of Vi typhoid vaccine in India, thrombomodulin mutations in atypical hemolytic-uremic syndrome, hearing improvement after bevacizumab in patients with neurofibromatosis type 2, effects of pay for performance on the quality of primary care in England, and a Medicare Part D update; a review article on ectopic pregnancy; a case report of a boy with headache, nausea, seizures, and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 3. This summary covers the issue of July 16, 2009. Featured are articles on endoscopic versus open vein-graft harvesting in coronary-artery bypass surgery, genotype disclosure and Alzheimer's disease, memory loss and the APOE E4 allele, capsule endoscopy versus colonoscopy for detecting polyps and cancer, and memory and the NMDA receptors; review articles on HPV vaccination for the prevention of cervical intraepithelial neoplasia and on a historical perspective on the emergence of influenza A ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 2. This summary covers the issue of July 9, 2009. Featured are articles on poly(ADP-ribose) polymerase inhibitor in BRCA-related cancer, raxibacumab for the treatment of inhalational anthrax, rates of serious infection after changes in regimens for medical abortion, lack of association between folate-receptor autoantibodies and neural-tube defects, an investigation of the cause of death in a gene-therapy trial, and limits on police use of bioidentifiers in Europe; a review article on screenin ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 361, No. 1. This summary covers the issue of July 2, 2009. Featured are articles on phospholipase A2 receptor in idiopathic membranous nephropathy, an epidemiologic study of in-hospital CPR in the elderly, preoperative staging of lung cancer with combined PET-CT, the effects of enalapril and losartan in type 1 diabetes, the effect of Medicare Part D on drug and medical spending, and cardiomyocyte renewal; a review article on rhabdomyolysis and acute kidney injury; a Clinical Problem-Solving article de ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 25. This summary covers the issue of June 18, 2009. Featured are articles on the emergence of a novel swine-origin influenza A (H1N1) virus in humans, triple-reassortant swine influenza A (H1) in humans in the United States, 2005-2009, evaluation of universal antenatal screening for group B streptococcus, immunodeficiency associated with FCN3 mutation and ficolin-3 deficiency, and a new target for tumor therapy; a review article on autologous hematopoietic stem-cell transplantation for multipl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 24. This summary covers the issue of June 11, 2009. Featured are articles on treatment for type 2 diabetes and coronary artery disease, duration of androgen suppression in the treatment of prostate cancer, safety of metaclopramide use in the first trimester of pregnancy, Zika virus outbreak on Yap Island, and primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants; a review article on prenatal screening for aneuploidy; a Clinical Problem-Solving article entitled Kiss of Deat ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 22. This summary covers the issue of May 28, 2009. Featured are articles on radiofrequency ablation in Barrett's esophagus with dysplasia; mutation in TET2 in myeloid cancers; age, neuropathology, and dementia; inactivating PAPSS2 mutations in a patient with premature pubarche; and handguns, health, and the Second Amendment; review articles on chronic venous insufficiency and varicose veins and on predisposing factors for adrenal insufficiency; a case report of a man with progressive neurologi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 21. This summary covers the issue of May 21, 2009. Featured are articles on early versus delayed invasive intervention in acute coronary syndromes, early glycoprotein IIb/IIIa inhibition in acute coronary syndromes, dipyridamole plus aspirin for hemodialysis graft patency, cost implications of reduced work hours and workloads for resident physicians, and mining rhinovirus sequencing; a review article on fomepizole for ethylene glycol and methanol poisoning; a case report of a pregnant woman wi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 20. This summary covers the issue of May 14, 2009. Featured are articles on adjuvant chemotherapy in older women with early-stage breast cancer, effect of clopidogrel added to aspirin in patients with atrial fibrillation, epinephrine and dexamethasone in children with bronchiolitis, antivenom for critically ill children with neurotoxicity from scorpion stings, and a fatal case of deer tick encephalitis; a review article on fungal nail disease; a case report of a man with coma after cardiac arr ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 19. This summary covers the issue of May 7, 2009. Featured are articles on long-term safety and efficacy of drug-eluting versus bare-metal stents in Sweden; paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction; epilepsy, ataxia, sensorineural deafness, tubulopathy, and KCNJ10 mutations; STIM1 mutation associated with a syndrome of immunodeficiency and autoimmunity; vaccine refusal and the risks of vaccine-preventable diseases; New York City's war on fat, and the or ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 18. This summary covers the issue of April 30, 2009. Featured are articles on CD4 count and antiretroviral therapy for HIV, telaprevir with peginterferon and ribavirin for chronic HCV infection, telaprevir and peginterferon with or without ribavirin for chronic HCV infection, rosuvastatin to prevent venous thromboembolism; review articles on asthma in pregnancy and on aspergillosis; a case report of a man with chest pain, dysphagia, and pleural and mediastinal calcifications; and Perspective a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 16. This summary covers the issue of April 16, 2009. Featured are articles on cognitive function at 3 years of age after fetal exposure to antiepileptic drugs, valsartan for prevention of recurrent atrial fibrillation, inhibitors of factor VIII in black patients with hemophilia, and electronic health records in U.S. hospitals; review articles on molar pregnancy and on genetics of type 1A diabetes; a case report of a man with migraine, aphasia, and hemiparesis and similarly affected family memb ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 15. This summary covers the issue of April 9, 2009. Featured are articles on efficacy of esomeprazole for treatment of poorly controlled asthma, brown adipose tissue in healthy adults, shifting terrain in the regulation of off-label promotion of pharmaceuticals, and fibrosis and myocardial infarction; a review article on myocarditis; a case report of a man with fever, headache, rash, and vomiting; and Perspective articles on stimulating the adoption of health information technology, on the NIH ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 14. This summary covers the issue of April 2, 2009. Featured are articles on cervical cancer in rural India, rosuvastatin and cardiovascular events in hemodialysis patients, cetuximab and chemotherapy for metastatic colorectal cancer, and rehospitalizations among Medicare patients; review articles on enuresis and on medical evaluation of patients undergoing electroconvulsive therapy; a Clinical Problem-Solving article describing a question well put; and Perspective articles on a to-do list for ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 12. This summary covers the issue of March 19, 2009. Featured are articles on racial differences in heart failure in young adults, vaccine prevention of maternal cytomegalovirus infection, genetic association with ovarian insufficiency, and genetic compensation in a human genomic disorder; review articles on carbon monoxide poisoning and on moyamoya disease; a case report of a man with massive rectal bleeding; and Perspective articles on the uncertain future for cardiovascular drug development ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 11. This summary covers the issue of March 12, 2009. Featured are articles on melamine-contaminated powdered formula and urolithiasis in young children; a test for arrhythmogenic right ventricular cardiomyopathy; long-term ozone exposure and mortality; a nonsimultaneous, extended altruistic-donor chain; growth in the care of older patients by hospitalists in the United States; and reversing artherosclerosis; a review article on primary open-angle glaucoma; a case report of a woman with headache ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 9. This summary covers the issue of February 26, 2009. Featured are articles on a comparison of weight-loss diets with different compositions of fat, protein, and carbohydrates, C3 polymorphisms and allograft outcome in renal transplantation, spermatogenesis in a man with complete deletion of USP9Y, emergence of ciprofloxacin-resistant Neisseria meningitidis in North America, and acute promyelocytic leukemia; review articles on excision and grafting of thermal burns and on preservation of fer ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 8. This summary covers the issue of February 19, 2009. Featured are articles on estimation of warfarin dose, IDH1 and IDH2 mutations in gliomas, quality of life after late invasive therapy for occluded arteries, implications of the globalization of clinical research, and progress and deficiencies in the registration of clinical trials; review articles on epistaxis and on gene-expression signatures in breast cancer; a case report of a woman with vertigo, facial weakness, and a generalized seiz ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 7. This summary covers the issue of February 12, 2009. Featured are articles on B-cell clones as early markers for chronic lymphocytic leukemia, effect of dronedarone on cardiovascular events in atrial fibrillation, endocrine therapy plus zoledronic acid in premenopausal breast cancer, long-term control of HIV by CCR5 Delta 32/Delta 32 stem-cell transplantation, financial incentives for smoking cessation, and stress and inflammatory bowel disease; a case report of a woman with a rash and numbn ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 6. This summary covers the issue of February 5, 2009. Featured are articles on chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer, breast cancer after estrogen plus progestin in postmenopausal women, respiratory syncytial virus infection in young children, mutations in SYNGAP1 in autosomal nonsyndromic mental retardation, and limits on Medicare's ability to control spending on cancer drugs; a review article on primary ovarian insufficiency; a Clinical Problem-Solving art ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 5. This summary covers the issue of January 29, 2009. Featured are articles on gene therapy for immunodeficiency due to adenosine deaminase deficiency, long-term consequences of kidney donation, deletion of IKZF1 and prognosis in acute lymphoblastic leukemia, weight loss to treat urinary incontinence in overweight and obese women, a surgical safety checklist to reduce morbidity and mortality in a global population, and a proteomic analysis of ischemic preconditioning; a review article on beha ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 3. This summary covers the issue of January 15, 2009. Featured are articles on fractional flow reserve versus angiography for guiding percutaneous coronary intervention, atypical antipsychotic drugs and the risk of sudden cardiac death, cumulative live-birth rates after in vitro fertilization, effect of pneumococcal conjugate vaccine on pneumococcal meningitis, peginterferon alfa-2a and ribavirin in Latino and non-Latino whites with hepatitis C, and oncogenesis and metastasis; a review articl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 2. This summary covers the issue of January 8, 2009. Featured are articles on timing of elective repeat cesarean delivery and neonatal outcomes, a strategy to control transmission of Schistosoma japonicum in China, glucose control and vascular complications in type 2 diabetes, arterial blood gases and oxygen content in climbers on Mount Everest, and mortality attributable to smoking in China; a review article on vitiligo; a case report of a man with progressive cognitive decline; and Perspect ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 360, No. 1. This summary covers the issue of January 1, 2009. Featured are articles on machine perfusion or cold storage in deceased-donor kidney transplantation, decontamination of the digestive tract and oropharynx in ICU patients, a syndrome with congenital neutropenia and mutations in G6PC3, modulation of blood pressure by central melanocortinergic pathways, giant osteoclast formation and long-term oral bisphosphonate therapy, and bacterial virulence and the living system; a review article on radi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 26. This summary covers the issue of December 25, 2008. Featured are articles on cognitive behavioral therapy and sertraline in childhood anxiety, genetic variants in diabetes and celiac disease, inhibition of the Bcl-xL deamidation pathway in myeloproliferative disorders, azathioprine or methotrexate maintenance for ANCA-associated vasculitis; review articles on acute pulmonary embolism and on the molecular basis of metastasis; a case report of a man with blurred vision; and Perspective artic ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 25. This summary covers the issue of December 18, 2008. Featured are articles on Dicer, Drosha, and outcomes in ovarian cancer, thrombolysis during resuscitation for out-of-hospital cardiac arrest, alfuzosin in chronic prostatitis-chronic pelvic pain syndrome, adverse reactions associated with contaminated heparin, PHD2 mutation and congenital erythrocytosis with paraganglioma, and boosting beta-cell numbers; a review article on temporomandibular disorders; a case report of a woman with spleno ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 24. This summary covers the issue of December 11, 2008. Featured are articles on the efficacy of RTS,S/AS01E vaccine against malaria in children 5 to 17 months of age, safety and immunogenicity of RTS,S/AS02D malaria vaccine in infants, combination antimalarial therapies in children, an obesity-associated FTO gene variant and increased energy intake in children, effect of aspirin or resistant starch on hereditary colorectal neoplasia; a review article on the prevention and treatment of seasona ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 23. This summary covers the issue of December 4, 2008. Featured are articles on benazepril plus amlodipine or hydrochlorothiazide for hypertension in high-risk patients, prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon, tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B, irbesartan in patients with heart failure and preserved ejection fraction, and proteinuria and immunity; a review article on levodopa for Parkinson's disease; a Clinica ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 22. This summary covers the issue of November 27, 2008. Featured are articles on stromal gene signatures in large-B-cell lymphomas, the diagnostic performance of coronary angiography by 64-row CT, a genetic link between developmental language disorders, and lessons about Medicare; review articles on primary retinal detachment and on infection in chronic obstructive pulmonary disease; a case report of a 17-year-old boy with a pituitary tumor and skull abnormalities; and Perspective articles on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 18. This summary covers the issue of October 30, 2008. Featured are articles on early insulin therapy in very-low-birth-weight infants, aggressive vs. conservative phototherapy for infants with extremely low birth weight, genetically elevated C-reactive protein and ischemic vascular disease, GAD treatment and insulin secretion in recent-onset type 1 diabetes, and patients' perception of hospital care in the United States; a review article on Clostridium difficile; a case report of a woman with ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 17. This summary covers the issue of October 23, 2008. Featured are articles on K-ras mutations and cetuximab in advanced colorectal cancer, donor TLR4 polymorphisms and aspergillosis in stem-cell transplantation, pulmonary-vein isolation for atrial fibrillation in patients with heart failure, alemtuzumab vs. interferon beta-1a in early multiple sclerosis, cardiovascular outcomes after a change in prescription policy for clopidogrel, and the exercise pill; a review article on uric acid and car ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 16. This summary covers the issue of October 16, 2008. Featured are articles on monovalent type 1 oral poliovirus vaccine in newborns, effectiveness of immunization against paralytic poliomyelitis in Nigeria, computer-aided detection for screening mammography, recurrent rearrangements of chromosome 1q21.1 and variable pediatric phenotypes; review articles on gastroesophageal reflux disease and on blunt aortic injury; a case report of a girl with recurrent oral lesions and cutaneous bullae; and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 15. This summary covers the issue of October 9, 2008. Featured are articles on a 4-year trial of tiotropium in COPD, effectiveness of maternal influenza immunization in mothers and infants, long-term follow-up after control of blood pressure in type 2 diabetes, 10-year follow-up of intensive glucose control in type 2 diabetes, and inflammation and influenza; a review article on breast reconstruction after surgery for breast cancer; a case report of a man with chest pain, arthralgias, and a med ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 14. This summary covers the issue of October 2, 2008. Featured are articles on maraviroc for previously treated patients with R5 HIV-1 infection, subgroup analyses of maraviroc in previously treated R5 HIV-1 infection, toll-like receptor 3 and geographic atrophy in age-related macular degeneration, continuous glucose monitoring and intensive treatment of type 1 diabetes, and lethal injection and the Constitution; review articles on autosomal dominant polycystic kidney disease and on hepatitis ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 13. This summary covers the issue of September 25, 2008. Featured are articles on thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke, drug-eluting or bare-metal stents for acute myocardial infarction, intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis, analyses of cancer data from three ezetimibe trials, and cell therapies for muscular dystrophy; a review article on lung cancer; a case report of a woman with a mass in the breast and a solitary lesion ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 12. This summary covers the issue of September 18, 2008. Featured are articles on the accuracy of CT colonography for detection of large adenomas and cancers, five-year risk of colorectal neoplasia after negative screening colonoscopy, telmisartan to prevent recurrent stroke and cardiovascular events, and aspirin and extended-release dipyridamole versus clopidogrel for recurrent stroke; review articles on food allergy and on platelets, petechiae, and preservation of the vascular wall; a case r ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week: Supplement to the New England Journal of Medicine, Vol. 359, No. 11. This summary covers the issue of September 11, 2008. Featured are articles on arthroscopic surgery for osteoarthritis of the knee, incidental meniscal findings on knee MRI in middle-aged and elderly persons, platinum-based chemotherapy plus cetuximab in head and neck cancer, NHERF1 mutations and responsiveness of renal parathyroid hormone, and turning thought into action; review articles on gonadotropin-releasing hormone agonists for endometriosis and on recent advances in head and neck ca ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 23. This summary covers the issue of June 5, 2008. Featured are articles on aliskiren combined with losartan in type 2 diabetes and nephropathy, hypothermia therapy in children with traumatic brain injury, contaminated heparin and activation of the contact system, socioeconomic inequalities in health in European countries, and metabolism and therapeutic angiogenesis; a review article on chemotherapy-induced nausea and vomiting; a Clinical Problem-Solving article describing a joint venture; and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM This Week - Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 22. This summary covers the issue of May 29, 2008. Featured are articles on aprotinin versus lysine analogues in high-risk cardiac surgery, methylnaltrexone for opioid-induced constipation in advanced illness, a placebo-controlled trial of prucalopride for severe chronic constipation, and multiple genetic loci for bone mineral density and fractures; review articles on precocious puberty and on the hepatopulmonary syndrome; a case report of a man with metastatic renal-cell carcinoma; and Perspe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 21. This summary covers the issue of May 22, 2008. Featured are articles on facilitated PCI in ST-elevation myocardial infarction, bivalirudin during PCI in acute myocardial infarction, gene therapy for Leber’s congenital amaurosis, the collective dynamics of smoking in a large social network, and how HIV guts the immune system; a review article on sublingual immunotherapy; a case report of a woman with bone pain; and Perspective articles on direct-to-consumer advertising of drug-eluting ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 20. This summary covers the issue of May 15, 2008. Featured are articles on class-sparing regimens for initial treatment of HIV-1 infection, biomarkers to predict death from cardiovascular causes, cardiac troponin in acute heart failure, recombinant activated factor VII for intracerebral hemorrhage; review articles on rotator-cuff failure and on biomarkers in heart failure; a case report of a man with an elevated PSA level and early-stage prostate cancer; and Perspective articles on vaccines, ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 19. This summary covers the issue of May 8, 2008. Featured are articles on hyperglycemia and adverse pregnancy outcomes, metformin plus insulin for the treatment of gestational diabetes, sudden cardiac arrest and early repolarization, left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia, an immunodeficiency disease with RAG mutations and granulomas, and targeting tumor angiogenesis; a review article on tumor angiogenesis; a case report of a man with an ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 18. This summary covers the issue of May 1, 2008. Featured are articles on hypertension in the very elderly, the shared genetic causes of childhood-onset cardiac hypertrophy, gene mutations and outcomes in cytogenetically normal AML, microRNA expression in cytogenetically normal AML, and a behavioral intervention to improve obstetrical care; a review article on the nonsurgical management of obesity in adults; a Clinical Problem-Solving article entitled "Back to Basics"; and Perspective article ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 17. This summary covers the issue of April 24, 2008. Featured are articles on stents versus coronary-artery bypass grafting for left main coronary artery disease, home AEDs for sudden cardiac arrest, pyruvate kinase deficiency and malaria, mutations in the iodotyrosine deiodinase gene and hypothyroidism, ezetimibe use in the United States and Canada, and mast cells and pancreatic cancer; a review article on artesunate for severe falciparum malaria; a case report of a man with rheumatoid arthri ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 16. This summary covers the issue of April 17, 2008. Featured are articles on weekly paclitaxel and breast cancer, intensive care for extremely premature newborns, YKL-40 levels and asthma, pharmaceutical promotion to physicians and first amendment rights, tectonic shifts in the health information economy, electronic health records and medical research, and grassroots activism and physician supply; review articles on the irritable bowel syndrome and on the management of very low birth weight; ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 15. This summary covers the issue of April 10, 2008. Featured are articles on telmisartan, ramipril, or both in high-risk vascular disease, acyclovir and the incidence of HIV infection among women in Tanzania, long-term results of carotid stenting versus endarterectomy, recent resurgence of mumps in the United States, legal and regulatory issues in medical outsourcing, and activated protein C and diabetic nephropathy; a review article on the challenge of HIV-1 subtype diversity; a case report ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 13. This summary covers the issue of March 27, 2008. Featured are articles on diaphragm disuse atrophy and mechanical ventilation, coronary calcium as a predictor of coronary events across four racial or ethnic groups, cervical length at mid-pregnancy and risk of cesarean delivery, drug-review deadlines and safety problems, and cardiac connections and preventing arrhythmia; review articles on hydroxurea for the treatment of sickle cell anemia and on cardiac plasticity; a case report of a girl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 11. This summary covers the issue of March 13, 2008. Featured are articles on anesthesia awareness and the bispectral index, cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose, DNA methylation markers and early recurrence in stage I lung cancer, VEGF inhibition and renal thrombotic microangiopathy, smoking and mortality among adults in India, and chemical immunosuppression in islet transplantation; review articles on epigenetics in cancer and on EGFR antagonists i ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 10. This summary covers the issue of March 6, 2008. Featured are articles on a new arenavirus in a cluster of fatal transplant-associated diseases, genetic determinants of response to warfarin during initial anticoagulation, a Parkinsonian syndrome in methcathinone users and the role of manganese, autoimmune polyendocrine syndrome type 1 and NALP5, and the coordination of care in the U.S. health care system; review articles on urinary stress incontinence in women and on acute pulmonary embolis ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 9. This summary covers the issue of February 28, 2008. Featured are articles on vasopressin versus norepinephrine infusion in patients with septic shock, severe anemia in Malawian children, two new susceptibility loci for systemic lupus erythematosus, cumulative association of five genetic variants with prostate cancer, and curing sickle cell anemia in a mouse model; review articles on phototherapy for neonatal jaundice and on systemic lupus erythematosus; a case report of a girl with chest p ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 8. This summary covers the issue of February 21, 2008. Featured are articles on aprotinin during coronary-artery bypass grafting and risk of death, the effect of aprotinin on outcome after coronary-artery bypass grafting, surgical versus nonsurgical treatment for lumbar spinal stenosis, hepatitis E virus and chronic hepatitis in organ-transplant recipients, and scientific and legal viability of follow-on protein drugs; a review article on lumbar spinal stenosis; a case report of a woman with ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 6. This summary covers the issue of February 7, 2008. Featured are articles on thrombus aspiration during primary percutaneous coronary intervention, HLA-B5701 screening for hypersensitivity to abacavir, the effect of a multifactorial intervention on mortality in type 2 diabetes, phenotype and course of Hutchinson-Gilford progeria syndrome, and neonatal diagnosis and treatment of Menkes disease; a review article on neurogenic orthostatic hypotension; a Clinical Problem-Solving article that as ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 4. This summary covers the issue of January 24, 2008. Featured are articles on drug-eluting stents vs. coronary-artery bypass grafting in multivessel coronary disease, a comparison of bare-metal and drug-eluting stents for off-label indications, HLA-mismatched renal transplantation without maintenance immunosuppression, tolerance and chimerism after renal and hematopoietic-cell transplantation, chimerism and tolerance in a recipient of a deceased-donor liver transplant, cost sharing and mammo ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 3. This summary covers the issue of January 17, 2008. Featured are articles on iron-overload–related disease in HFE hereditary hemochromatosis, a citywide protocol for primary PCI in ST-segment elevation myocardial infarction, etanercept for plaque psoriasis in children and adolescents, selective publication of antidepressant trials, rules for donations to tissue banks, and guiding aerosol deposition in the lung; a review article on avian influenza in humans; an interactive Clinical Decisions ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 2. This summary covers the issue of January 10, 2008. Featured are articles on hydrocortisone for septic shock, intensive insulin therapy and pentastarch resuscitation in severe sepsis, sirolimus for angiomyolipoma in tuberous sclerosis or lymphangioleiomyomatosis, outcomes in athletes with marked ECG repolarization abnormalities, and an HIF2A mutation in familial erythrocytosis; a review article on the long-QT syndrome; a case report of a man with sudden onset of abdominal pain and hypotens ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 358, No. 1. This summary covers the issue of January 3, 2008. Featured are articles on delayed time to defibrillation after in-hospital cardiac arrest; functional outcome after language mapping for glioma resection; platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis; capecitabine and oxaliplatin for advanced esophagogastric cancer; and B-cell identity; review articles on metformin for the treatment of the polycystic ovary syndrome and on major depressive disorder; a Clinical Probl ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 26. This summary covers the issue of December 27, 2007. Featured are articles on catheter ablation for the prevention of defibrillator therapy; paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer; local dystrophin restoration with PRO051; COL4A1 mutations and hereditary angiopathy, nephropathy, aneurysms, and muscle cramps; and military-civilian collaboration in trauma care and the senior visiting surgeon program; a review article on localized prostate cancer; a ca ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 25. This summary covers the issue of December 20, 2007. Featured are articles on breast cancer stromal cells with TP53 mutations and nodal metastases, TP53 mutations and survival in squamous-cell carcinoma of the head and neck, reduced exposure to calcineurin inhibitors in renal transplantation, telbivudine versus lamivudine in patients with chronic hepatitis B, outcomes of care by hospitalists, general internists, and family physicians, and small RNAs and large DNA viruses; a review article o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 24. This summary covers the issue of December 13, 2007. Featured are articles on dexamethasone in Vietnamese adolescents and adults with bacterial meningitis, corticosteroids for bacterial meningitis in adults in sub-Saharan Africa, outcomes 18 months after partial face transplantation, cardiac-resynchronization therapy in heart failure with narrow QRS complexes, and rapid expansion of the health workforce in response to the HIV epidemic; review articles on erectile dysfunction and on platelet ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 23. This summary covers the issue of December 6, 2007. Featured are articles on childhood body-mass index and the risk of coronary heart disease in adulthood, air quality and attenuated age-related decline in lung function, respiratory effects of exposure to diesel traffic in persons with asthma, metabolic effects of tesamorelin in patients with HIV, adolescent overweight and future adult coronary heart disease, and molecules that mediate mood; a review article on cochlear implants for childre ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 22. This summary covers the issue of November 29, 2007. Featured are articles on eltrombopag for thrombocytopenia in cirrhosis associated with hepatitis C, eltrombopag and chronic idiopathic thrombocytopenic purpura, rosuvastatin in older patients with systolic heart failure, and patent foramen ovale and cryptogenic stroke in older patients; review articles on late-life depression and on CT scans and radiation exposure; a case report of a man with left ventricular dysfunction after heart trans ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 21. This summary covers the issue of November 22, 2007. Featured are articles on torcetrapib in patients at high risk for coronary events, lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma, lung transplantation and survival in children with cystic fibrosis, the reporting of subgroup analyses in clinical trials, and the liver X receptor and atherosclerosis; a review article on sarcoidosis; a case report of a woman with rash, fever, and hypotension; and Perspective arti ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 20. This summary covers the issue of November 15, 2007. Featured are articles on prasugrel vs. clopidogrel in acute coronary syndromes, a chitinase-like protein in the lung and circulation in patients with severe asthma, teriparatide or alendronate in glucocorticoid-induced osteoporosis, cetuximab for the treatment of colorectal cancer, and the anatomy of medical school patenting; a review article on diverticulitis; a case report of a man with inflammatory bowel disease and recent onset of fev ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 19. This summary covers the issue of November 8, 2007. Featured are articles on the long-term effects of caffeine for apnea of prematurity, duration of humoral immunity to common viral and vaccine antigens, chemotherapy plus involved-field radiation in early-stage Hodgkin's disease, abnormal brain development in newborns with congenital heart disease, and hepatocellular carcinoma and sex; review articles on electroconvulsive therapy for depression and on chronic lung disease after premature bi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 18. This summary covers the issue of November 1, 2007. Featured are articles on zoledronic acid in reducing mortality after hip fracture, adjuvant chemotherapy for gastric cancer with S-1, incidental findings on brain MRI in the general population, and visualizing out-of-body experience in the brain; review articles on the assessment of patients' competence to consent to treatment and on leukotrienes; a Clinical Problem-Solving article describing a condition that is no respecter of age; and Pe ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 17. This summary covers the issue of October 25, 2007. Featured are articles on hepatitis A vaccine versus immune globulin for postexposure prophylaxis; cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer; addition of insulin to oral therapy in type 2 diabetes; and reversing scarring in the heart; a review article on celiac disease; a case report of an HIV-positive man with anemia; an interactive Clinical Decisions featuring the management of stable coronary disease; an ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 16. This summary covers the issue of October 18, 2007. Featured are articles on HPV DNA and Pap tests to screen for cervical cancer, early treatment with prednisolone or acyclovir in Bell's palsy, and STAT3 mutations in the hyper-IgE syndrome; review articles on hair loss in women and on the time to treatment in primary percutaneous coronary intervention; a case report of a woman with a second breast cancer; and Perspective articles on Medicare's new reimbursement rule and on "payment by resul ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 15. This summary covers the issue of October 11, 2007. Featured are articles on a long-term follow-up of the West of Scotland Coronary Prevention Study, airway bacteria in neonates and childhood asthma, HER2 expression and response to paclitaxel in node-positive breast cancer, cardiomyopathy and exercise intolerance in muscle glycogen storage disease 0, quality of ambulatory care delivered to children in the United States, and myocardial repair and periostin; a review article on ursodeoxycholi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 14. This summary covers the issue of October 4, 2007. Featured are articles on the effectiveness of influenza vaccination in the community-dwelling elderly, donepezil for the treatment of agitation in Alzheimer's disease, effectiveness and safety of drug-eluting stents, and CT colonography versus colonoscopy for the detection of advanced neoplasia; review articles on osteoarthritis of the hip and on a critical appraisal of "chronic lyme disease"; a Clinical Problem-Solving article describing n ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 13. This summary covers the issue of September 27, 2007. Featured are articles on early thimerosal exposure and neuropsychological outcomes at 7 to 10 years, antibodies against MICA antigens and kidney-transplant rejection, cardiovascular events and very low levels of LDL cholesterol, evidence of MEN-2 in the original description of classic pheochromocytoma, viral latency and the immune response, and on harnessing the power of default options to improve health care; a review article on uremia; ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 12. This summary covers the issue of September 20, 2007. Featured are articles on long-term outcomes after repeat doses of antenatal corticosteroids, TRAF1-C5 as a risk locus for rheumatoid arthritis, a polymorphism in the CTGF promoter region associated with systemic sclerosis, and improving the health of the American people; a review article on gynecomastia; a case report of man with gastric cancer and lung nodules; and Perspective articles on health care for all and on a eulogy for a qualit ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 11. This summary covers the issue of September 13, 2007. Featured are articles on diesel-exhaust inhalation in men with coronary disease, high-dose melphalan versus melphalan plus dexamethasone for AL amyloidosis, idraparinux versus standard therapy for venous thromboembolic disease, extended prophylaxis of venous thromboembolism with idraparinux, and prions, proteasomes, and mad cows; review articles on low-tidal-volume ventilation in ARDS and on myocardial reperfusion injury; a case report o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 10. This summary covers the issue of September 6, 2007. Featured are articles on epoetin alfa in critically ill patients, STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus, dronedarone for the maintenance of sinus rhythm in atrial fibrillation or flutter, minimizing ventricular pacing to reduce atrial fibrillation in sinus-node disease, and sustaining the engine of U.S. biomedical discovery; review articles on hypertriglyceridemia and on the control of neglected tropic ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 9. This summary covers the issue of August 30, 2007. Featured are articles on risk alleles for multiple sclerosis identified by a genomewide study, reversal of idiopathic hypogonadotropic hypogonadism, saline or albumin for fluid resuscitation in traumatic brain injury, use of a continuous-flow device in patients awaiting heart transplantation, luteinizing hormone beta mutation and hypogonadism, and a tale about tau; a review article on the mechanisms of anabolic therapies for osteoporosis; a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 8. This summary covers the issue of August 23, 2007. Featured are articles on the effects of bariatric surgery on mortality in Sweden, long-term mortality after gastric bypass surgery, a study of sexuality and health among older U.S. adults, a genomewide analysis of sporadic amyotrophic lateral sclerosis; review articles on isolated systolic hypertension in the elderly and on normotensive ischemic acute renal failure; a case report of a man with recurrent fevers; and Perspective articles on h ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 7. This summary covers the issue of August 16, 2007. Featured are articles on a genetic risk factor for periodic limb movements in sleep, medical abortion and the risk of subsequent pregnancy outcomes, sonification of removed hip and knee prostheses for the diagnosis of infection, prophylactic cranial irradiation in extensive small-cell lung cancer, a decade of direct-to-consumer prescription-drug advertising, and adherent invasive E. coli and Crohn's disease; a review article on psoralen and ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 6. This summary covers the issue of August 9, 2007. Featured are articles on prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia, rituximab for the treatment of severe pemphigus, complement C3 variant and age-related macular degeneration, NXY-059 for acute ischemic stroke, and the tension between needing to improve care and knowing how to do it; review articles on acute ischemic stroke and on drug-induced immune thrombocytopenia; a case report of a pr ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 3. This summary covers the issue of July 19, 2007. Featured are articles on oral anticoagulant and antiplatelet therapy and peripheral arterial disease, certolizumab pegol for the treatment of Crohn's disease, maintenance therapy with certolizumab pegol for Crohn's disease, trends in the use of intracytoplasmic sperm injection in the United States, and rational design of cancer-drug combinations; review articles on BCR-ABL tyrosine kinase inhibitors for chronic myelogenous leukemia and on vit ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 2. This summary covers the issue of July 12, 2007. Featured are articles on clinical outcomes of breast cancer in carriers of BRCA1 and BRCA2 mutations, peginterferon alfa-2a and ribavirin for 16 or 24 weeks in hepatitis C virus genotype 2 or 3, neural-tube defects and folic acid fortification in Canada, use of health services by previously uninsured Medicare beneficiaries, and primary care and pay for performance in England; a review article on the management of an inherited predisposition t ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 357, No. 1. This summary covers the issue of July 4, 2007. Featured are articles on first-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects, needlestick injuries among surgeons in training, allogeneic bone marrow transplantation in mevalonic aciduria, and industry sponsors' obligations to their research subjects; review articles on arteriovenous malformations of the brain and on disclosing harmful medical errors to patients; a case report of a boy with a calcified ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 26. This summary covers the issue of June 28, 2007. Featured are articles on first-trimester use of selective serotonin-reuptake inhibitors and the risk of birth defects, needlestick injuries among surgeons in training, allogeneic bone marrow transplantation in mevalonic aciduria, and industry sponsors' obligations to their research subjects; review articles on arteriovenous malformations of the brain and on disclosing harmful medical errors to patients; a case report of a boy with a calcified ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 25. This summary covers the issue of June 21, 2007. Featured are articles on injectable paromomycin for visceral leishmaniasis in India, the clinical course and prognosis of smoldering (asymptomatic) multiple myeloma, estrogen therapy and coronary-artery calcification, the natural history of multiple sclerosis with childhood onset, entecavir inhibition of HIV-1 replication, and microRNAs and the failing heart; a review article on natalizumab for multiple sclerosis; a case report of a college s ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 21. This summary covers the issue of May 24, 2007. Featured are articles on aspirin and the risk of colorectal cancer in relation to the expression of COX-2, Burch colposuspension versus fascial sling to reduce urinary stress incontinence, advanced life support for out-of-hospital respiratory distress, level and volume of neonatal intensive care and mortality among very-low-birth-weight infants, the Supreme Court and abortion rights, and tanning and p53; a review article on bariatric surgery f ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 20. This summary covers the issue of May 17, 2007. Featured are articles on strategies for reducing treatment in mild persistent asthma, rescue use of beclomethasone and albuterol in mild asthma, and glucose regulation in young adults with very low birth weight; review articles on the syndrome of inappropriate antidiuresis and on evolving concepts on an HIV vaccine; a case report of a woman with asthma and cardiorespiratory arrest; an interactive Clinical Decisions article on the treatment of ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 19. This summary covers the issue of May 10, 2007. Featured are articles on a quadrivalent vaccine against HPV to prevent high-grade cervical lesions, a quadrivalent vaccine against HPV to prevent anogenital diseases, a case-control study of HPV and oropharyngeal cancer, end-of-life practices in the Netherlands under the euthanasia act, and cancer regression by senescence; a review article on sodium and potassium in the pathogenesis of hypertension; a case report of a man with fever and pain a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 18. This summary covers the issue of May 3, 2007. Featured are articles on once-yearly zoledronic acid for postmenopausal osteoporosis, intracoronary streptokinase after primary percutaneous coronary intervention, age at surgery for undescended testis and risk of testicular cancer, long-term effect of diabetes and its treatment on cognitive function, and use of physician's services under Medicare's resource-based payments; a review article on superior vena cava syndrome with malignant causes; ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 17. This summary covers the issue of April 26, 2007. Featured are articles on adjunctive antidepressant treatments for bipolar depression, class of antiretroviral drugs and the risk of myocardial infarction, a lethal defect of mitochondrial and peroxisomal fission, physician-industry relationships, and the many roads to vaccine immunity; a review article on continuous positive airway pressure for obstructive sleep apnea; a video showing orotracheal intubation; a case report of a woman with gy ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 16. This summary covers the issue of April 19, 2007. Featured are articles on tranfusion strategies in pediatric intensive care units, the effect of torcetrapib on carotid atherosclerosis in familial hypercholesterolemia, omeprazole before endoscopy in patients with gastrointestinal bleeding, targeted therapy for inherited GPI deficiency, and the decrease in breast-cancer incidence in 2003 in the United States; a review article on fecal incontinence in adults; a case report of a woman with re ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 15. This summary covers the issue of April 12, 2007. Featured are articles on optimal medical therapy with or without PCI for stable coronary disease, interleukin-1-receptor antagonist in type 2 diabetes mellitus, radiotherapy for glioblastoma in the elderly, inactivated poliovirus vaccine in Cuba, and retinal progenitor cells; a review article on strategies for safer liver surgery and partial liver transplantation; a case report of a man with neck pain, weakness in the arms, and cranial-nerve ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 14. This summary covers the issue of April 5, 2007. Featured are articles on computer-aided detection in screening mammography, invariant natural killer T cells in asthma and COPD, vitamins and perinatal outcomes among HIV-negative women in Tanzania, and mutations in VANGL1 associated with neural-tube defects; review articles on prophylaxis for thromboembolism in hospitalized medical patients and on viral hepatitis in HIV infection; a clinical problem-solving article on building a diagnosis f ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 13. This summary covers the issue of March 29, 2007. Featured are articles on MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer, effect of torcetrapib on the progression of coronary atherosclerosis, telomerase mutations in familial idiopathic pulmonary fibrosis, bronchial thermoplasty in asthma, and new insights on idiopathic pulmonary fibrosis; review articles on the varicella-zoster vaccine for the prevention of herpes zoster and on the withdrawal of a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 12. This summary covers the issue of March 22, 2007. Featured are articles on emergency duties and deaths from heart disease among U.S. firefighters, NALP1 in vitiligo-associated multiple autoimmune disease, neurodevelopment and cognition in children after enterovirus 71 infection, and redarkening of laser-treated port-wine stains; a review article on intermittent claudication; a case report of a woman with pain and swelling of the legs; and Perspective articles on HIV in India, on revising Me ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 11. This summary covers the issue of March 15, 2007. Featured are articles on weekend versus weekday admission and mortality from myocardial infarction, allografting as compared with autografting for newly diagnosed myeloma, loss of vaccine-induced immunity to varicella over time, care patterns in Medicare and implications for pay for performance, and structural variation in the human genome; a review article on the failing heart; a case report of a man with chest pain followed by cardiac arr ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 10. This summary covers the issue of March 8, 2007. Featured are articles on a pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents, safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents, long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden, stent thrombosis in randomized clinical trials of drug-eluting stents, analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents, and the ethical challenges pos ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 9. This summary covers the issue of March 1, 2007. Featured are articles on the safety and efficacy of a recombinant hepatitis E vaccine, vancomycin-induced immune thrombocytopenia, treatment of periodontitis and endothelial function, improving the management of chronic disease at community health centers, and leveraging the delivery of liposomes to tumors; a review article on amiodarone for atrial fibrillation; a clinical problem-solving article entitled "Into the Woods"; and Perspective art ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 8. This summary covers the issue of February 22, 2007. Featured are articles on salmeterol and fluticasone propionate and survival in COPD, reduction of HIV-1 RNA levels with therapy to suppress herpes simplex virus, DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer, missense mutations in the BCS1L gene as a cause of the Bjornstad syndrome, and new models of clinical clerkships; review articles on diabetic gastroparesis and on coronary microvascular dysfunction; a case report of a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 7. This summary covers the issue of February 15, 2007. Featured are articles on pulsed corticosteroid therapy for primary treatment of Kawasaki disease, endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis, live attenuated versus inactivated influenza vaccine in infants and young children, inheritance of a cancer-associated MLH1 germ-line epimutation, Medicaid revisited, and a closer look at follicular lymphoma; a review article on perioperative stroke; a case re ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 6. This summary covers the issue of February 8, 2007. Featured are articles on clomiphene, metformin, or both for infertility in the polycystic ovary syndrome; GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis; interleukin-12/23 monoclonal antibody for the treatment of psoriasis; religion, conscience, and controversial clinical practices; and the regulatory and judicial oversight of nonprofit hospitals; a review article on the incidentally discovered adrenal m ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 5. his summary covers the issue of February 1, 2007. Featured are articles on air pollution and cardiovascular events in women, new JAK2 mutations in polycythemia vera and idiopathic erythrocytosis, a communication strategy and brochure for relatives of patients dying in the ICU, prepubertal gynecomastia and lavender and tea tree oils, public reporting and pay for performance in hospital quality improvement, and a link between proposed mechanisms of Huntington's disease; a review article on i ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 4. This summary covers the issue of January 25, 2007. Featured are articles on posaconazole or fluconazole in graft-versus-host disease, posaconazole versus fluconazole or itraconazole prophylaxis in patients with neutropenia, uterine-artery embolization versus surgery for symptomatic fibroids, lack of association between antimyelin antibodies and progression to multiple sclerosis; review articles on in vitro fertilization and on assessment in medical education; a case report of a boy with re ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 2. This summary covers the issue of January 11, 2007. Featured are articles on sunitinib versus interferon alfa in metastatic renal-cell carcinoma, sorafenib in advanced clear-cell renal-cell carcinoma, response to antiretroviral therapy after one peripartum dose of nevirapine, inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia, and the risk of death for former prison inmates; a review article on concussion; a case report of a woman with epistaxis, hemate ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 356, No. 1. This summary covers the issue of January 4, 2007. Featured are articles on a five-gene signature and survival in non-small-cell lung cancer, multidrug-resistant Salmonella enterica serotype Typhimurium associated with pet rodents, dopamine agonists and the risk of cardiac-valve regurgitation, valvular heart disease during treatment with dopamine agonists; review articles on primary PCI for myocardial infarction with ST-segment elevation and on Whipple's disease; a clinical problem-solving ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 26. This summary covers the issue of December 28, 2006. Featured are articles on decreasing catheter-related bloodstream infections in the ICU, lapatinib plus capecitabine for HER2-positive advanced breast cancer, female predominance and transmission distortion in the long-QT syndrome, T. evansi infection in humans, and deficiency of cartilage-associated protein in recessive lethal osteogenesis imperfecta; a review article on monoclonal gammopathy of undetermined significance; a case report of ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 25. This summary covers the issue of December 21, 2006. Featured are articles on diagnostic techniques for ventilator-associated pneumonia, biomarkers for the prediction of cardiovascular events and death, ertapenem versus cefotetan prophylaxis in elective colorectal surgery, PET of brain amyloid and tau in mild cognitive impairment, and protein turnover and Alzheimer's disease; review articles on teaching surgical skills and on autoimmune pancreatitis; a case report of a woman with systemic l ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 24. This summary covers the issue of December 14, 2006. Featured are articles on the prevention of antigenically drifted influenza by inactivated and live attenuated vaccines, the effectiveness of school-based influenza vaccination, colonoscopic withdrawal times and adenoma detection during screening colonoscopy, paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer; review articles on adenomatous polyps of the colon and on acromegaly; a case report of a boy with hea ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 23. This summary covers the issue of December 7, 2006. Featured are articles on coronary intervention for persistent occlusion after myocardial infarction, five-year follow-up of patients receiving imatinib for chronic myeloid leukemia, K. oxytoca in antibiotic-associated colitis, glycemic durability of rosiglitazone, metformin, or glyburide monotherapy, and imatinib mesylate and the heart; review articles on peginterferon and ribavirin for chronic hepatitis C and on the myeloproliferative di ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 18. This summary covers the issue of November 2, 2006. Featured are articles on epirubicin and cyclophosphamide, methotrexate, and fluorouracil as adjuvant therapy for early breast cancer, colonoscopy in colorectal-cancer screening for detection of advanced neoplasia, left ventricular assist device and drug therapy to reverse heart failure, treatment of periodontal disease and the risk of preterm birth, pay for performance in commercial HMOs, and voters and health care in the 2006 election; a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 17. This summary covers the issue of October 26, 2006. Featured are articles on survival of patients with stage I lung cancer detected on CT screening, rituximab and intravenous immune globulin for pemphigus vulgaris, D-dimer testing to determine the duration of anticoagulation therapy, the genotype of the original Wiskott phenotype, and the reversal of myotonia in myotonic dystrophy; review articles on teaching professionalism in medical education and on pemphigus, bullous impetigo, and the ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 16. This summary covers the issue of October 19, 2006. Featured are articles on DHEA in elderly women and DHEA or testosterone in elderly men, endarterectomy versus stenting in patients with symptomatic severe carotid stenosis, AMG 531 in immune thrombocytopenic purpura, reduced lung function at birth and the risk of asthma at 10 years of age, and FDA regulation of stem-cell-based therapies; review articles on chronic prostatitis and the chronic pelvic pain syndrome and on the management of s ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 15. This summary covers the issue of October 12, 2006. Featured are articles on the effectiveness of atypical antipsychotic drugs in patients with Alzheimer's disease, microscopic-observation drug-susceptibility assay for the diagnosis of tuberculosis, effect of ramipril on the incidence of diabetes, a self-regulation program for maintenance of weight loss, chronic health conditions in adult survivors of childhood cancer, and the role of microglia in amytorophic lateral sclerosis; a review ar ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 14. This summary covers the issue of October 5, 2006. Featured are articles on ranibizumab for age-related macular degeneration, ranibizumab versus verteporfin for age-related macular degeneration, immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis, lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion; review articles on the prevention of mengingococcal disease and on age-related macular degeneration; a clinical problem-solving article ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 13. This summary covers the issue of September 28, 2006. Featured are articles on sentinel-node biopsy or nodal observation in melanoma, an international trial of the Edmonton protocol for islet transplantation, transmission of human herpesvirus 8 by blood transfusion, hunger strikes at Guantanamo, and a key role for a viral lytic gene in Kaposi's sarcoma; review articles on American medical education 100 years after the Flexner report and on the tuberous sclerosis complex; a case report of a ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 12. This summary covers the issue of September 21, 2006. Featured are articles on intracoronary injection of bone marrow cells in acute myocardial infarction, intracoronary bone marrow-derived progenitor cells in acute myocardial infarction, transcoronary transplantation of progenitor cells after myocardial infarction, eculizumab in paroxysmal nocturnal hemoglobinuria; review articles on acute vulvovaginitis and on cancer stem cells; a case report of a woman with painful nodules on the finger ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 11. This summary covers the issue of September 14, 2006. Featured are articles on sirolimus-eluting stents versus uncoated stents in acute myocardial infarction, paclitaxel-eluting versus uncoated stents in primary percutaneous coronary intervention, chemotherapy with preoperative radiotherapy in rectal cancer, oral fingolimod for relapsing multiple sclerosis, cost-effectiveness of HIV treatment in resource-poor settings, and gram-negative bacteria and secretion of toxins; a review article on ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 10. This summary covers the issue of September 7, 2006. Featured are articles on DNA repair by ERCC1 in non-small-cell lung cancer and adjuvant chemotherapy, soluble endoglin and other circulating antiangiogenic factors in preeclampsia, enoxaparin versus unfractionated heparin in elective PCI, cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412; review articles on social anxiety disorder and on oncogene-induced cell senescence; a clinical problem-solving article des ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 8. This summary covers the issue of August 24, 2006. Featured are articles on overweight, obesity, and the risk of death among persons 50 to 71 years old, body-mass index and mortality in Korean men and women, aneurysm syndromes caused by mutations in the TGF-beta receptor, predicting death in Chagas' heart disease; review articles on heparin-induced thrombocytopenia and on dystonia; a case report of a woman with difficulty walking; and Perspective articles on imposing personal responsibilit ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 7. This summary covers the issue of August 17, 2006. Featured are articles on daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus, methicillin-resistant S. aureus infections among patients in the emergency department, alendronate or alfacalcidol in glucocorticoid-induced osteoporosis, neonatal MRI to predict neurodevelopmental outcomes in preterm infants, gradient of disability across the U.S. socioeconomic spectrum, and on the mobilization of t ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 4. This summary covers the issue of July 27, 2006. Featured are articles on inhaled nitric oxide in preterm infants undergoing mechanical ventilation, early inhaled nitric oxide therapy in premature newborns with respiratory failure, counseling plus buprenorphine-naloxone maintenance therapy for opioid dependence, pay-for-performance programs in family practices in the United Kingdom, and on the troubled transformation of Britain's National Health Service; a review article on resistant or di ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 2. This summary covers the issue of July 13, 2006. Featured are articles on the effects of raloxifene on cardiovascular events and breast cancer, parental heart failure and heart-failure risk in offspring, postexposure doxycycline to prevent tick-borne relapsing fever, Doppler ultrasonography versus amniocentesis to predict fetal anemia, and employer-sponsored health care; review articles on recurrent aphthous stomatitis and on the intensive care of patients with HIV infection; a case report ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 355, No. 1. This summary covers the issue of July 6, 2006. Featured are articles on perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer, carbon in airway macrophages and lung function in children, the underrecognized burden of influenza in young children, hospital volume and the outcomes of mechanical ventilation, a reversal of type 1 diabetes in mice, and on employer-sponsored health insurance in the United States; a review article on melanoma; a Clinical Problem-S ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 25. This summary covers the issue of June 22, 2006. Featured are articles on condom use and the risk of genital HPV infection in young women, cyclophosphamide in scleroderma lung disease, stimulatory autoantibodies to the PDGF receptor in systemic sclerosis, connexin 40 gene mutations in atrial fibrillation, bioterror and bioart, and on TGF-beta; signaling, vascular remodeling, and hypertension; a review article on omalizumab for asthma; a case report of a boy with rapid growth of subcutaneou ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 24. This summary covers the issue of June 15, 2006. Featured are articles on dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias, nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL, retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects, a comparison of two fluid-management strategies in acute lung injury, and obesity as the new frontier of public health law; a review article on idiopathic short stature; a case r ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 23. This summary covers the issue of June 8, 2006. Featured are articles on a biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling, molecular diagnosis of Burkitt's lymphoma, major congenital malformations after first-trimester exposure to ACE inhibitors, single dose azithromycin for the treatment of cholera in adults, and a better way for cancer cells to die; review articles on microarray analysis and tumor classification and on measured and estimated glomerul ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 22. his summary covers the issue of June 1, 2006. Featured are articles on multidetector computed tomography for acute pulmonary embolism, outcomes of in-hospital ventricular fibrillation in children, body-mass index and symptoms of gastroesophageal reflux in women, and unintended consequences of caps on Medicare drug benefits; review articles on panic disorder and on ambulatory blood-pressure monitoring; a case report that emphasizes thinking outside the box; and Perspective articles on the ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 21. This summary covers the issue of May 25, 2006. Featured are articles on pulmonary-artery versus central venous catheter to guide treatment of acute lung injury, peritoneal drainage versus laparotomy for necrotizing enterocolitis in infants, transmission of LCMV infection by organ transplantation, a new immune cell and the response to imatinib mesylate, and evolution in the classroom and the courtroom; a review article on bone quality; a video in clinical medicine demonstrating male urethr ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 20. This summary covers the issue of May 18, 2006. Featured are articles on HER2 and responsiveness to adjuvant chemotherapy, caffeine therapy for apnea of prematurity, progressive volume increase in polycystic kidney disease, language ability after early detection of hearing impairment; review articles on acute pancreatitis and on the detection of prelingual hearing loss; a case report of a woman with sudden onset of abdominal distention; and Perspective articles on health care reform in Mas ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 19. This summary covers the issue of May 11, 2006. Featured are articles on inhaled corticosteroids and asthma in preschool children, inhaled corticosteroids in infants with wheezing, altered bone and mineral metabolism in patients receiving imatinib, the influence of donor C3 allotype on late renal-transplantation outcome, the regression of aortic aneurysms through pharmacologic therapy, claims, errors, and compensation in medical malpractice litigation and improving the quality of care thro ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 18. This summary covers the issue of May 4, 2006. Featured are articles on balloon angioplasty versus nitinol stents, children with elevated bilirubin levels, an antibody-deficiency syndrome due to mutations in the CD19 gene, inherited and somatic CD3-zeta mutations in a patient with T-cell deficiency, and the current state of medical education; a review article on thrombotic thrombocytopenic purpura; a clinical problem-solving article entitled "Ring around the Diagnosis"; and Perspective art ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 16. This summary covers the issue of April 20, 2006. Featured are articles on the efficacy and safety of corticosteroids for persistent ARDS, a therapeutic intervention for prehypertension, oral ondansetron for gastroenteritis in a pediatric emergency department, clopidogrel and aspirin versus aspirin alone to prevent atherothrombotic events; a review article on scabies; a case report of a man with hemoptysis and a pulmonary infiltrate; and Perspective articles on private health care in Canad ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 14. This summary covers the issue of April 6, 2006. Featured are articles on the effect of the pneumococcal conjugate vaccine on drug-resistant Streptococcus pneumoniae, a comparison of fondaparinux with enoxaparin in acute coronary syndromes, a comparison of enoxaparin with unfractionated heparin with fibrinolysis for myocardial infarction, the role of genetic mutation in small-vessel disease and hemorrhagic stroke; review articles on sexual desire and arousal disorders in women and on the b ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 13. This summary covers the issue of March 30, 2006. Featured are articles on an avian influenza vaccine, gatifloxacin therapy and dysglycemia, the prevalance of monoclonal gammopathy of undetermined significance among persons 50 years of age or older, genetic association between epilepsy and developmental regression, behavorial health insurance parity for federal employees, and targeting rickettsia; a review article on hereditary proteinuria syndromes; a case report of a woman with Barrett's ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 12. This summary covers the issue of March 23, 2006. Featured are articles on buproprion, sertraline, or venlafaxine after the failure of SSRIs for depression, medication augmentation after the failure of SSRIs for depression, ACAT inhibition and coronary atherosclerosis, genetic variants and protection against coronary heart disease; review articles on optic neuritis and on pregnancy in recipients of solid-organ transplants; a Sounding Board article on ethical considerations related to pregn ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 11. This summary covers the issue of March 16, 2006. Featured are articles on CD4+ cells and invariant T-cell receptor-positive natural killer T cells in asthma, maintenance treatment of major depression in old age, transfer of single blastocyst-stage and cleavage-stage embryos for in vitro fertilization, microRNAs as therapeutic targets, and the differences among socioeconomic subgroups in the quality of health care poor-quality health care; review articles on delirium in older persons and o ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 9. This summary covers the issue of March 2, 2006. Featured are articles on natalizumab alone and in combination with interferon for relapsing multiple sclerosis, evaluation of patients treated with natalizumab for PML, catheter ablation for chronic atrial fibrillation, and silencing herpes simplex virus with a vaginal microbicide; a review of the plaque and its pathogenesis in MS; a case report on a search for complications; and Perspective articles on facial transplantation and improving he ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 8. This summary covers the issue of February 23, 2006. Featured are articles on glucosamine and chondroitin sulfate for osteoarthritis of the knee, docetaxel or vinorelbine for breast cancer, denosumab in postmenopausal women with low bone mineral density, itopride in functional dyspepsia, and strategies for improving surgical quality; a review of osteoarthritis of the knee; a case report describing a 71-year-old woman with urinary incontinence and a mass in the bladder; and Perspective arti ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 7. This summary covers the issue of February 16, 2006. Featured are articles on calcium plus vitamin D supplementation and the risk of fractures and of colorectal cancer, evidence of a role for TNF-alpha in refractory asthma, autoimmunity during treatment of melanoma with interferon, spousal hospitalization and partner mortality, and understanding how NSAIDs work in colon cancer; a review of drug-related hepatotoxicity; a case report describing a girl with loss of vision in the right eye; an ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 6. This summary covers the issue of February 9, 2006. Featured are articles on saw palmetto for benign prostatic hyperplasia, radiotherapy plus cetuximab for head and neck cancer, SSRIs in pregnancy and persistent pulmonary hypertension of the newborn, and NXY-059 for acute ischemic stroke; review articles on antibiotic allergy and on chemokines and chemokine receptors in inflammation; a case report describing a woman with myalgias, fatigue, and shortness of breath; Perspective articles on fa ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 5. This summary covers the issue of February 2, 2006. Featured are articles on intensive insulin therapy during medical intensive care, human botulism immune globulin for infant botulism, risperidone augmentation of clozapine in schizophrenia, and endodermal cells from stem cells; review articles on coronary-artery stents and PET to assess cancer therapy; a Clinical Problem-Solving article on empirical therapy; and Perspective articles on home testing for HIV, expanding HIV testing in develo ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 3. This summary covers the issue of January 19, 2006. Featured are articles on inhaled hypertonic saline and cystic fibrosis, tenofovir and emtricitabine vs. zidovudine and lamivudine for HIV, prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch Syndrome; a review article on estrogen carcinogenesis in breast cancer; a case report of an HIV-positive man with rectal pain; recent research on targeting virulence; and Perspective articles on noma and malnutrition in Niger. ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 2. This summary covers the issue of January 12, 2006. Featured are articles on the causes of illness in returned travelers, benazepril for advanced chronic renal insufficiency, inhaled cyclosporine in lung-transplant recipients, and familial sinus bradycardia and a mutation in the cardiac pacemaker channel; review articles on chronic daily headache and acute lymphoblastic leukemia; a case report of a male lung-transplant recipient with fever, cough, hemoptysis, and abdominal pain; a Sounding ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 354, No. 1. This summary covers the issue of January 5, 2006. Featured are articles on a G1P[8] rotavirus vaccine, a human-bovine reassortant rotavirus vaccine, cisplatin and paclitaxel in ovarian cancer, and inhibiting inflammation in rheumatoid arthritis; review articles on bacterial meningitis and autoimmune hepatitis; a case describing a clinical "needle in a haystack"; and Perspective articles on the DEA and end-of-life care, searching the medical literature, and behavior and genes. Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 26. This summary covers the issue of December 29, 2005. Featured are articles on letrozole or tamoxifen for breast cancer, rescue angioplasty after failed thrombolytic therapy, transfusion and stroke in sickle cell disease, registration at ClinicalTrials.gov, and acute pulmonary edema; a case discussion of a man with mandibular swelling; and Perspective articles on the Medicare drug benefit. Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 25. This summary covers the issue of December 22, 2005. Featured are articles on intensive diabetes treatment and cardiovascular disease, T cells and early metastasis in colorectal cancer, oseltamivir resistance in avian influenza, unprofessional behavior in medical school, and inhaled nitric oxide therapy in adults, a case discussion of a woman with syphilis and persistent eosinophilia, recent research on ultraviolet A radiation and squamous-cell carcinoma, and Perspective articles on oselta ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 24. This summary covers the issue of December 15, 2005. Featured are articles on contraceptive methods and systemic lupus erythematosus, fatal influenza in children, atrial overdrive pacing for sleep apnea, and hirsutism, a case discussion of a pregnant woman with the nephrotic syndrome and hypertension, a discussion of the appropriate use of artificial nutrition and hydration, and Perspective articles on Guantanamo Bay and medical ethics and on influenza as an interpandemic and pandemic disea ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 23. This summary covers the issue of December 8, 2005. Featured are articles on C. difficile, febuxostat versus allopurinol for gout, infliximab for ulcerative colitis, renal-cell carcinoma, a case discussion of a man with cardiac arrest while sleeping, recent research on heme transport, and Perspective articles on the Nobel Prize and H. pylori, on Robert Koch and tuberculosis, on the medical detectives, and on remembering Berton Roueche. Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 22. This summary covers the issue of December 1, 2005. Featured in this issue are articles on antiretroviral therapy in Haiti, public health principles and the HIV epidemic, the risk of death associated with conventional vs. atypical antipsychotic medications, FOXP3 mRNA and renal allograft rejection, C. sordellii after medical abortion, patent foramen ovale, low-dose aspirin and atherothrombosis, a Clinical Problem-Solving article entitled A Hole in the Argument and Perspective articles on mi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 21. This summary covers the issue of November 24, 2005. Featured in this issue are articles on mycophenolate for lupus nephritis, acetylcysteine in idiopathic pulmonary fibrosis, chromosome 1p and 11q deletions in neuroblastoma, beta-blockers and esophageal varices, basal-cell carcinoma, a case report describing a woman with seizure and altered mental state, California's medical-marijuana law, inducing intestinal growth, and Perspective articles on lessons from the 1918 influenza virus, biomedi ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 20. This summary covers the issue of November 17, 2005. Featured in this issue are articles on lifestyle modification and pharmacotherapy for obesity, rimonabant for obese patients, genetic distinctions among melanomas, sildenafil citrate therapy for pulmonary arterial hypertension, cervical-cancer screening in developing countries, long-acting methods of contraception, a case describing a woman with breast cancer and tumor cells in a sentinel lymph node, and a perspective article on balancing ... Listen | Listen in your iPhone | Download | View full cache | Visit Website NEJM Audio Summary: Supplement to the New England Journal of Medicine, Vol. 353, No. 19. This summary covers our issue of November 10, 2005. Featured in this issue are articles on screening for Down's syndrome, glioblastomas and EGFR kinase inhibitors, sleep apnea, oxygen-sensing mechanisms, a case report on a girl with a bullous skin eruption, health-information altruism, commensal bacteria and immunity, and personal metrics for physicians in practice. 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