Link to the Show / Show Notes This summary covers the issue of August 30, 2007. Featured are articles on risk alleles for multiple sclerosis identified by a genomewide study, reversal of idiopathic hypogonadotropic hypogonadism, saline or albumin for fluid resuscitation in traumatic brain injury, use of a continuous-flow device in patients awaiting heart transplantation, luteinizing hormone beta mutation and hypogonadism, and a tale about tau; a review article on the mechanisms of anabolic therapies for osteoporosis; a case report of a pregnant woman with intrauterine fetal death, and Perspective articles on the regulation of follow-on biologics, on rosiglitazone and lessons from an FDA advisory committee meeting, and on cardiac mechanical support.