Link to the Show / Show NotesThis summary covers the issue of December 10, 2009. Featured are articles on allogeneic hematopoietic stem-cell transplantation for sickle cell disease, platelet inhibition with cangrelor in patients undergoing PCI, and dabigatran vs. warfarin for acute venous thromboembolism; a review article on telomere diseases; a case report of a boy with paroxysmal headaches and visual changes; and Perspective articles on two essential elements of delivery-system reform; on the Supreme Court, process patents, and medical innovation; and on the breadth of hopes.