Link to the Show / Show Notes This summary covers the issue of February 4, 2010. Featured are articles on a placebo-controlled study of oral fingolimod in relapsing multiple sclerosis, oral fingolimod or intramuscular interferon for relapsing multiple sclerosis, cladribine or placebo for relapsing multiple sclerosis, acyclovir and transmission of HIV-1 from persons infected with HIV-1 and HSV-2, and comparative effectiveness and health care spending; a review article on jet lag; a Clinical Problem-Solving article describing a woman with dyspnea; and Perspective articles on Medicare and medical technology, on withholding information from patients, and on launching HITECH.