Link to the Show / Show Notes This summary covers the issue of September 28, 2006. Featured are articles on sentinel-node biopsy or nodal observation in melanoma, an international trial of the Edmonton protocol for islet transplantation, transmission of human herpesvirus 8 by blood transfusion, hunger strikes at Guantanamo, and a key role for a viral lytic gene in Kaposi's sarcoma; review articles on American medical education 100 years after the Flexner report and on the tuberous sclerosis complex; a case report of a man with dyspnea, fever, and lymphadenopathy; and Perspective articles on corporate payoffs and the future of Plavix, on crisis in the emergency department, and on the continuing risk of transfusion-transmitted infections.